Evidence map›Paper›PMID 28100787›Full record

ArticleThe Journal of biological chemistry2017

Polymorphic Variants of Human Protein l-Isoaspartyl Methyltransferase Affect Catalytic Activity, Aggregation, and Thermal Stability: IMPLICATIONS FOR THE ETIOLOGY OF NEUROLOGICAL DISORDERS AND COGNITIVE AGING.

Charity Juang, Baihe Chen, Jean-Louis Bru, Katherine Nguyen, Eric Huynh, Mahsa Momen, Jeungjin Kim, Dana W Aswad

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. PCMT1 as a prognostic marker in breast cancer.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2025
    Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Charity JuangFrom the Department of Molecular Biology and Biochemistry, University of California Irvine, Irvine, California 92697-3900.
Baihe ChenFrom the Department of Molecular Biology and Biochemistry, University of California Irvine, Irvine, California 92697-3900.
Jean-Louis BruFrom the Department of Molecular Biology and Biochemistry, University of California Irvine, Irvine, California 92697-3900.
Katherine NguyenFrom the Department of Molecular Biology and Biochemistry, University of California Irvine, Irvine, California 92697-3900.
Eric HuynhFrom the Department of Molecular Biology and Biochemistry, University of California Irvine, Irvine, California 92697-3900.
Mahsa MomenFrom the Department of Molecular Biology and Biochemistry, University of California Irvine, Irvine, California 92697-3900.
Jeungjin KimFrom the Department of Molecular Biology and Biochemistry, University of California Irvine, Irvine, California 92697-3900.
Dana W AswadFrom the Department of Molecular Biology and Biochemistry, University of California Irvine, Irvine, California 92697-3900 dwaswad@uci.edu.ORCID 0000-0001-5098-3461
University of California, Irvine · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Protein l-isoaspartyl methyltransferase (PIMT/PCMT1), a product of the human

Indexed as

Cognitive AgingAllelesBrainCatalysisComputational BiologyEpilepsyFluorometryGenotypeHumansIsoaspartic AcidMutationNervous System DiseasesPolymorphism, Single NucleotideProtein D-Aspartate-L-Isoaspartate MethyltransferaseSequence Analysis, DNATemperatureIsoaspartic AcidProtein D-Aspartate-L-Isoaspartate Methyltransferaseepilepsygenetic polymorphismneurological diseaseprotein aggregationprotein methylationprotein stabilityrecombinant protein expressionS-adenosylmethionine (SAM)

Identifiers

PMID28100787
PMCPMC5339750
OpenAlexW2577131430

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.