ArticleJournal of neurophysiology2017
Minocycline blocks glial cell activation and ventilatory acclimatization to hypoxia.
Article in Journal of neurophysiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 40 citations in OpenAlex.
- Influence of chronic hypoxia on the hypoxic ventilatory response of juvenile and adult rats.Respiratory physiology & neurobiology · 2023Article
- Chronic intermittent hypoxia enhances glycinergic inhibition in nucleus tractus solitarius.Journal of neurophysiology · 2022Article
- Role of microglia in blood pressure and respiratory responses to acute hypoxic exposure in rats.The journal of physiological sciences : JPS · 2022Article
- Characterization of Astrocytes in the Minocycline-Administered Mouse Photothrombotic Ischemic Stroke Model.Neurochemical research · 2022Article
- Time Domains of Hypoxia Responses and -Omics Insights.Frontiers in physiology · 2022Review
- Unilateral vagotomy alters astrocyte and microglial morphology in the nucleus tractus solitarii of the rat.American journal of physiology. Regulatory, integrative and comparative physiology · 2021Article
- The role of astrocytes in the nucleus tractus solitarii in maintaining central control of autonomic function.American journal of physiology. Regulatory, integrative and comparative physiology · 2021Review
- Sex- and Region-Specific Differences in the Transcriptomes of Rat Microglia from the Brainstem and Cervical Spinal Cord.The Journal of pharmacology and experimental therapeutics · 2020Article
- Astrocytes in the nucleus of the solitary tract: Contributions to neural circuits controlling physiology.Physiology & behavior · 2020Review
- Ventilatory and carotid body responses to acute hypoxia in rats exposed to chronic hypoxia during the first and second postnatal weeks.Respiratory physiology & neurobiology · 2020Article
- Sustained Hypoxia Alters nTS Glutamatergic Signaling and Expression and Function of Excitatory Amino Acid Transporters.Neuroscience · 2020Article
- Pulmonary hypertension: Pathophysiology beyond the lung.Pharmacological research · 2020Review
- DTI Study on Brain Structure and Cognitive Function in Patients with Chronic Mountain Sickness.Scientific reports · 2019Article
- Neuroinflammation in the NTS is associated with changes in cardiovascular reflexes during systemic inflammation.Journal of neuroinflammation · 2019Article
- Hyperexcitability and plasticity induced by sustained hypoxia on rectus abdominis motoneurons.The Journal of physiology · 2019Article
- Lung-injury depresses glutamatergic synaptic transmission in the nucleus tractus solitarii via discrete age-dependent mechanisms in neonatal rats.Brain, behavior, and immunity · 2018Article
- Short-Term Sustained Hypoxia Elevates Basal and Hypoxia-Induced Ventilation but Not the Carotid Body Chemoreceptor Activity in Rats.Frontiers in physiology · 2018Article
- Contribution of Oxidative Stress and Inflammation to the Neurogenic Hypertension Induced by Intermittent Hypoxia.Frontiers in physiology · 2018Review
- Minocycline Has Anti-inflammatory Effects and Reduces Cytotoxicity in anJournal of virology · 2017Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 2 countries.
Funding
Abstract
Ventilatory acclimatization to hypoxia (VAH) is the time-dependent increase in ventilation, which persists upon return to normoxia and involves plasticity in both central nervous system respiratory centers and peripheral chemoreceptors. We investigated the role of glial cells in VAH in male Sprague-Dawley rats using minocycline, an antibiotic that inhibits microglia activation and has anti-inflammatory properties, and barometric pressure plethysmography to measure ventilation. Rats received either minocycline (45mg/kg ip daily) or saline beginning 1 day before and during 7 days of chronic hypoxia (CH, Pi
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.