Evidence map›Paper›PMID 28100637›Full record

ArticleMolecular biology of the cell2017

A Zip3-like protein plays a role in crossover formation in the SC-less meiosis of the protist

Anura Shodhan, Kensuke Kataoka, Kazufumi Mochizuki, Maria Novatchkova, Josef Loidl

Abstract read
In one paragraph

Article in Molecular biology of the cell, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 16 citations in OpenAlex.

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  13. BIME2, a novel gene required for interhomolog meiotic recombination in the protist model organism Tetrahymena.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Anura ShodhanDepartment of Chromosome Biology, University of Vienna, Vienna Biocenter, 1030 Vienna, Austria.
Kensuke KataokaInstitute of Molecular Biotechnology of the Austrian Academy of Sciences and.
Kazufumi MochizukiInstitute of Molecular Biotechnology of the Austrian Academy of Sciences and.
Maria NovatchkovaInstitute of Molecular Biotechnology of the Austrian Academy of Sciences and.
Josef LoidlDepartment of Chromosome Biology, University of Vienna, Vienna Biocenter, 1030 Vienna, Austria josef.loidl@univie.ac.at.
Institute of Molecular Biotechnology · ATUniversity of Vienna · AT

Funding

Austrian Science Fund FWF P 27313
6 · The paper itself

Abstract

When programmed meiotic DNA double-strand breaks (DSBs) undergo recombinational repair, genetic crossovers (COs) may be formed. A certain level of this is required for the faithful segregation of chromosomes, but the majority of DSBs are processed toward a safer alternative, namely noncrossovers (NCOs), via nonreciprocal DNA exchange. At the crossroads between these two DSB fates is the Msh4-Msh5 (MutSγ) complex, which stabilizes CO-destined recombination intermediates and members of the Zip3/RNF212 family of RING finger proteins, which in turn stabilize MutSγ. These proteins function in the context of the synaptonemal complex (SC) and mainly act on SC-dependent COs. Here we show that in the SC-less ciliate

Indexed as

Cell Cycle ProteinsChromosomal Proteins, Non-HistoneCrossing Over, GeneticDNA-Binding ProteinsDNA Breaks, Double-StrandedDNA RepairMeiosisRecombination, GeneticRING Finger DomainsSynaptonemal ComplexTetrahymenaCell Cycle ProteinsChromosomal Proteins, Non-HistoneDNA-Binding Proteins

Identifiers

PMID28100637
PMCPMC5349789
OpenAlexW2575448376

What OpenQuestion holds

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LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.