Evidence map›Paper›PMID 28100613›Full record

ArticleJournal of virology2017

Dynamic Modulation of Expression of Lentiviral Restriction Factors in Primary CD4

Andrew R Rahmberg, Premeela A Rajakumar, James M Billingsley, R Paul Johnson

Open access · bronzeAbstract read
In one paragraph

Article in Journal of virology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.3field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Andrew R RahmbergVirology Program, Harvard University, Graduate School of Arts and Sciences, Division of Medical Science, Boston, Massachusetts, USA.
Premeela A RajakumarYerkes National Primate Research Center, Atlanta, Georgia, USA.
James M BillingsleyYerkes National Primate Research Center, Atlanta, Georgia, USA.
R Paul JohnsonYerkes National Primate Research Center, Atlanta, Georgia, USA rpaul.johnson@emory.edu.
New England Biolabs (United States) · USEmory National Primate Research Center

Funding

LC: HIV Vaccine Trials NetworkUM1AI068618 · NIAID · FRED HUTCHINSON CANCER RESEARCH CENTER · PI Margaret Juliana McElrath · 2011 to 2026
$483.6M
Yerkes National Primate Research Center Role of type-I IFN in regulating COVID-19 induced inflammation and pathogenesisP51OD011132 · OD · EMORY UNIVERSITY · PI Joon Sup Lee · 2012 to 2026
$167.0M
Virology and Molecular Biomarkers CoreP30AI050409 · NIAID · EMORY UNIVERSITY · PI Ann M Chahroudi, Colleen F Kelley · 2002 to 2026
$74.0M
New England Primate Research Center Base GrantP51OD011103 · OD · HARVARD MEDICAL SCHOOL · PI FLIER, JEFFREY S · 2012 to 2013
$24.7M
SPF Breeding Colonies at the Yerkes NPRCU24OD011023 · OD · EMORY UNIVERSITY · PI COHEN, JOYCE KIMBERLY · 2012 to 2017
$8.2M
NIAID NIH HHS P30 AI050409NIAID NIH HHS UM1 AI068618NIH HHS P51 OD011103NIH HHS P51 OD011132NIH HHS U24 OD011023
6 · The paper itself

Abstract

Although multiple restriction factors have been shown to inhibit HIV/SIV replication, little is known about their expression

Indexed as

AnimalsCD4-Positive T-LymphocytesCells, CulturedGene Expression RegulationImmunity, InnateJejunumMacaca mulattaSimian Acquired Immunodeficiency SyndromeSimian Immunodeficiency VirusTranscriptomeCD4+ T lymphocytesgut-associated lymphoid tissueinterferon-stimulated genesrestriction factorssimian immunodeficiency virus

Identifiers

PMID28100613
PMCPMC5355611
OpenAlexW2574542930

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.