Evidence map›Paper›PMID 28100609›Full record

ArticleJournal of virology2017

Sterol Binding by the Tombusviral Replication Proteins Is Essential for Replication in Yeast and Plants.

Kai Xu, Peter D Nagy

Open access · bronzeAbstract read
In one paragraph

Article in Journal of virology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
9.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 39 citations in OpenAlex.

  1. Article
  2. Novel endornaviruses infectingThe Journal of general virology · 2025
    Article
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  6. Review
  7. Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. The retromer is co-opted to deliver lipid enzymes for the biogenesis of lipid-enriched tombusviral replication organelles.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Kai XuDepartment of Plant Pathology, University of Kentucky, Lexington, Kentucky, USA.
Peter D NagyDepartment of Plant Pathology, University of Kentucky, Lexington, Kentucky, USA pdnagy2@uky.edu.
University of Kentucky · US

Funding

Mechanism of inhibition of RNA virus replication by host WW-domain proteinsR21AI109529 · NIAID · UNIVERSITY OF KENTUCKY · PI NAGY, PETER · 2014 to 2015
$385k
Blocking RNA virus replication through the antiviral functions of cellular helicasesR21AI122078 · NIAID · UNIVERSITY OF KENTUCKY · PI NAGY, PETER · 2016 to 2017
$385k
NIAID NIH HHS R21 AI109529NIAID NIH HHS R21 AI122078
6 · The paper itself

Abstract

Membranous structures derived from various organelles are important for replication of plus-stranded RNA viruses. Although the important roles of co-opted host proteins in RNA virus replication have been appreciated for a decade, the equally important functions of cellular lipids in virus replication have been gaining full attention only recently. Previous work with

Indexed as

Amino Acid SequenceBinding SitesCholesterolMembrane MicrodomainsNicotianaProtein BindingProtoplastsSaccharomyces cerevisiaeTombusvirusViral ProteinsVirus ReplicationCholesterolViral Proteinslipidsmembrane bindingplantRNA replicationsterolTBSVtombusvirusvirus-host interactionsyeast

Identifiers

PMID28100609
PMCPMC5355592
OpenAlexW2578709657

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.