Evidence map›Paper›PMID 28100585›Full record

ArticleGenome research2017

Fast and accurate de novo genome assembly from long uncorrected reads.

Robert Vaser, Ivan Sović, Niranjan Nagarajan, Mile Šikić

Abstract read
In one paragraph

Article in Genome research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1,914 papers.

0numbers the graph read from it
0cells of the map it votes in
1,914citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1,914 citing papers in PubMed.

  1. Nanopore Sequencing for Chikungunya Virus: Principles and Application.Methods in molecular biology (Clifton, N.J.) · 2027
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  16. Complete genome sequence ofMicrobiology resource announcements · 2026
    Article
  17. Telomere-to-Telomere Genome Assemblies ofJournal of fungi (Basel, Switzerland) · 2026
    Article
  18. Article
  19. Article
  20. Draft genome sequence ofMicrobiology resource announcements · 2026
    Article

1,854 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Robert VaserDepartment of Electronic Systems and Information Processing, University of Zagreb, Faculty of Electrical Engineering and Computing, 10000 Zagreb, Croatia.
Ivan SovićCentre for Informatics and Computing, Ruđer Bošković Institute, 10000 Zagreb, Croatia.
Niranjan NagarajanGenome Institute of Singapore, Singapore 138672, Singapore.
Mile ŠikićDepartment of Electronic Systems and Information Processing, University of Zagreb, Faculty of Electrical Engineering and Computing, 10000 Zagreb, Croatia.ORCID 0000-0002-8370-0891

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The assembly of long reads from Pacific Biosciences and Oxford Nanopore Technologies typically requires resource-intensive error-correction and consensus-generation steps to obtain high-quality assemblies. We show that the error-correction step can be omitted and that high-quality consensus sequences can be generated efficiently with a SIMD-accelerated, partial-order alignment-based, stand-alone consensus module called Racon. Based on tests with PacBio and Oxford Nanopore data sets, we show that Racon coupled with miniasm enables consensus genomes with similar or better quality than state-of-the-art methods while being an order of magnitude faster.

Indexed as

AlgorithmsContig MappingGenomicsSequence AlignmentSequence Analysis, DNA

Identifiers

PMID28100585
PMCPMC5411768

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.