Observational studyBMJ open2017
Prevalence and clinical impact of recreational drug consumption in people living with HIV on treatment: a cross-sectional study.
Observational study in BMJ open, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 42 citations in OpenAlex.
- Trends in Mortality in People With HIV From 1999 through 2020: A Multicohort Collaboration.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2024Article
- Using Intervention Mapping to Develop an mHealth Intervention to Support Men Who Have Sex With Men Engaging in Chemsex (Budd): Development and Usability Study.JMIR research protocols · 2022Article
- Glutamine antagonist JHU083 improves psychosocial behavior and sleep deficits in EcoHIV-infected mice.Brain, behavior, & immunity - health · 2022Article
- Risky Sexual Practices, Sexually Transmitted Infections, Motivations, and Mental Health among Heterosexual Women and Men Who Practice Sexualized Drug Use in Spain.International journal of environmental research and public health · 2022Article
- Polysubstance use and adherence to antiretroviral treatment in the Miami Adult Studies on HIV (MASH) cohort.AIDS care · 2022Article
- Recreational Drug Use in People Living with HIV in Spain: Factors Associated with Drug Use and the Impact on Clinical Outcomes.AIDS and behavior · 2021Article
- Characteristics and Longitudinal Patterns of Erectile Dysfunction Drug Use Among Men Who Have Sex with Men in the U.S.Archives of sexual behavior · 2021Article
- Chemsex Practices and Health-Related Quality of Life in Spanish Men with HIV Who Have Sex with Men.Journal of clinical medicine · 2021Article
- High frequency of potential phosphodiesterase type 5 inhibitor drug interactions in males with HIV infection and erectile dysfunction.PloS one · 2021Observational
- Article
- Harm Reduction Practices and Needs in a Belgian Chemsex Context: Findings from a Qualitative Study.International journal of environmental research and public health · 2020Article
- Drug use and antiretroviral therapy (ART) interactions: a qualitative study to explore the knowledge, beliefs, adherence, and quality of life of people living with HIV taking ART and illicit drugs.AIDS research and therapy · 2020Article
- Depression, lifestyle factors and cognitive function in people living with HIV and comparable HIV-negative controls.HIV medicine · 2019Article
- Inconsistent condom use between serodifferent sexual partnerships to the human immunodeficiency virus.Revista latino-americana de enfermagem · 2019Article
- Prevalence and patterns of illicit drug use in people living with HIV in Spain: A cross-sectional study.PloS one · 2019Observational
- Prevalence and Associations of Illicit Drug and Polydrug Use in People Living with HIV in Vienna.Scientific reports · 2018Article
- Low levels of chemsex among men who have sex with men, but high levels of risk among men who engage in chemsex: analysis of a cross-sectional online survey across four countries.Sexual health · 2018Article
- Human Immunodeficiency Virus and Trans Women: A Literature Review.Transgender health · 2018Review
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesDrug interactions, poor adherence to medication and high-risk sexual behaviour may occur in individuals with HIV using recreational drugs. Thus, we aimed to assess the prevalence of recreational drugs use and to explore its clinical impact in HIV patients on treatment.
methodsObservational, cross sectional, study conducted in a 700 bed university hospital, Barcelona, Spain. A total of 208 adults living with HIV on treatment were included. A questionnaire was administered by clinical pharmacists, including evaluation of sociodemographic variables, past 12-month drug consumption, adherence to antiretrovirals (Simplified Medication Adherence Questionnaire) and high-risk sexual behaviour (condomless sex/multiple partners). Additional data were obtained from clinical records. Recreational drug-antiretroviral interactions were checked in reference databases. Prevalence was calculated for 5% precision and 95% CI. Crude and adjusted binary logistic regressions were performed to identify associations between recreational drug use and adherence problems, and between recreational drug use and high-risk sexual behaviour.
resultsFrom the overall sample, 92 participants (44.2%) consumed recreational drugs over the past 1 year. Of these, 44 (48.8%) had used different types of recreational drugs in this period. We detected 11 recreational substances, including sildenafil and nitrites. The most consumed drugs were: cannabis (68.5%), cocaine (45.5%), nitrites (31.5%), sildenafil (28.3) and ecstasy (19.6%). Relevant interactions occurred in 46 (50%) of the individuals consuming drugs. Recreational drug consumption was found to be related to adherence problems with antiretrovirals (OR: 2.51 (95% CI 1.32 to 4.77) p=0.005) and high-risk sexual behaviour (OR: 2.81 (95% CI 1.47 to 5.39) p=0.002).
conclusionsRecreational drugs are frequently used by HIV patients on treatment. Classical drugs and new substances consumed in sexual context are usual. Recreational drug consumption interferes with several clinical outcomes, including potentially relevant interactions between drugs and antiretrovirals, adherence problems and high-risk sexual behaviour. Thus, there is the urgent need of implementing patient-centred care involving recreational drug consumption.
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