Trial reportHeart (British Cardiac Society)2017
Oscillatory whole-body vibration improves exercise capacity and physical performance in pulmonary arterial hypertension: a randomised clinical study.
Trial report in Heart (British Cardiac Society), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 18 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Influence of Training With Whole Body Vibration Device (Galileo) on Quality of Life (QoL), Exercise Capacity, as Well as on the Effects of Muscle Power and Muscle Function in Patients With Pulmonal Arterial Hypertension (PAH). (GALILEO PAH)
Observation of Acute Cardiopulmonary Effects in Healthy Individuals Performing Cardiopulmonary Exercise Test (CPX) During Whole Body Vibration (WBV)
Who cites it
18 citing papers in PubMed, 6 syntheses or guidelines pooled it, 46 citations in OpenAlex.
- Quality of life in patients with pulmonary arterial hypertension: A systematic review and meta-analysis.Health and quality of life outcomes · 2026Pooled it
- Safety and efficacy of exercise training in patients with pulmonary hypertension: a systematic review and meta-analysis.European journal of applied physiology · 2026Pooled it
- Selection of patient-reported outcome measures in pulmonary arterial hypertension clinical trials: a systematic review, meta-analysis and health-related quality of life framework.European respiratory review : an official journal of the European Respiratory Society · 2025Pooled it
- Exercise-based rehabilitation programmes for pulmonary hypertension.The Cochrane database of systematic reviews · 2023Pooled it
- The effect of whole body vibration on health-related quality of life in patients with chronic conditions: a systematic review.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2019Pooled it
- Long-Term Effects of Whole-Body Vibration on Human Gait: A Systematic Review and Meta-Analysis.Frontiers in neurology · 2019Pooled it
- Whole body vibration training during allogeneic hematopoietic cell transplantation-the effects on patients' physical capacity.Annals of hematology · 2020Trial
- Impact of whole-body vibration training on gait in patients with progressive multiple sclerosis: a pilot randomised study.BMJ neurology open · 2026Article
- Safety and effectiveness of oscillatory whole-body vibration training on exercise capacity and physical performance in aortic valve stenosis patients prior to transcatheter aortic valve implantation: a randomized clinical trial.Clinical research in cardiology : official journal of the German Cardiac Society · 2025Article
- Review
- Exercise Capacity and Ventilatory Efficiency in Patients With Pulmonary Arterial Hypertension.Journal of the American Heart Association · 2023Article
- A Pre-Post Study on the Cardiorespiratory Response to Different Protocols of Exposure on a Vibratory Platform in Young Healthy Individuals.International journal of environmental research and public health · 2022Article
- The Use of Vibration Training in Men after Myocardial Infarction.International journal of environmental research and public health · 2022Article
- Editorial: Non-pharmacologic Sustained Endothelial Shear Stress: An Evolving Clinical Paradigm.Frontiers in physiology · 2021Article
- Effects of Different Types of Exercise Training on Pulmonary Arterial Hypertension: A Systematic Review.Journal of clinical medicine · 2020Review
- Bone in heart failure.Journal of cachexia, sarcopenia and muscle · 2020Review
- Effects of flexi bar training model to health-related physical fitness in overweight adults.Journal of physical therapy science · 2020Article
- How whole-body vibration can help our COPD patients. Physiological changes at different vibration frequencies.International journal of chronic obstructive pulmonary diseaseArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveIn patients with pulmonary arterial hypertension (PAH), supportive therapies may be beneficial in addition to targeted medical treatment. Here, we evaluated the effectiveness and safety of oscillatory whole-body vibration (WBV) in patients on stable PAH therapy.
methodsTwenty-two patients with PAH (mean PAP≥25 mm Hg and pulmonary arterial wedge pressure (PAWP)≤15 mm Hg) who were in world health organization (WHO)-Functional Class II or III and on stable PAH therapy for≥3 months, were randomised to receive WBV (16 sessions of 1-hour duration within 4 weeks) or to a control group, that subsequently received WBV. Follow-up measures included the 6-min walking distance (6MWD), cardiopulmonary exercise testing (CPET), echocardiography, muscle-power, and health-related quality of life (HRQoL; SF-36 and LPH questionnaires).
resultsWhen compared to the control group, patients receiving WBV exhibited a significant improvement in the primary endpoint, the 6MWD (+35.4±10.9 vs -4.4±7.6 m), resulting in a net benefit of 39.7±7.8 m (p=0.004). WBV was also associated with substantial improvements in CPET variables, muscle power, and HRQoL. The combined analysis of all patients (n=22) indicated significant net improvements versus baseline in the 6MWD (+38.6 m), peakVO2 (+65.7 mL/min), anaerobic threshold (+40.9 mL VO
conclusionsWBV substantially improves exercise capacity, physical performance, and HRQoL in patients with PAH who are on stable targeted therapy. This methodology may be utilised in structured training programmes, and may be feasible for continuous long-term physical exercise in these patients. TRIAL REGISTRATION NUMBER: NCT01763112; Results.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.