Evidence map›Paper›PMID 28100466›Full record

ArticleAmerican journal of epidemiology2017

Associations of Accelerometer-Measured and Self-Reported Sedentary Time With Leukocyte Telomere Length in Older Women.

Aladdin H Shadyab, Caroline A Macera, Richard A Shaffer, Sonia Jain, Linda C Gallo, Michael J LaMonte, Alexander P Reiner, Charles Kooperberg, Cara L Carty, Chongzhi Di and 3 more

Open access · bronzeAbstract read
In one paragraph

Article in American journal of epidemiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Prolonged exposure to leisure screen time notably accelerates biological aging: Evidence from observational studies and genetic associations.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2025
    Observational
  6. Review
  7. Review
  8. Review
  9. Review
  10. Article
  11. Article
  12. Why are there associations between telomere length and behaviour?Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2018
    Article
  13. Association of Accelerometer-Measured Physical Activity With Leukocyte Telomere Length Among Older Women.The journals of gerontology. Series A, Biological sciences and medical sciences · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Aladdin H Shadyab
Caroline A Macera
Richard A Shaffer
Sonia Jain
Linda C Gallo
Michael J LaMonte
Alexander P Reiner
Charles Kooperberg
Cara L Carty
Chongzhi Di
Todd M Manini
Lifang Hou
Andrea Z LaCroix
University of California, San Diego · US

Funding

University of Buffalo Clinical and Translational Science Institute - Supplement SchulyerUL1TR001412 · NCATS · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI MURPHY, TIMOTHY F · 2015 to 2024
$33.8M
University of Florida Older Americans Independence Center (OAIC)P30AG028740 · NIA · UNIVERSITY OF FLORIDA · PI CHRISTIAAN LEEUWENBURGH · 2007 to 2026
$22.8M
Objective Physical Activity and Cardiovascular Health in Women Aged 80 and OlderR01HL105065 · NHLBI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI LACROIX, ANDREA Z. · 2011 to 2014
$5.0M
Rheumatic Diseases Research Training GrantT32AR064194 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GARY S FIRESTEIN, Monica Guma · 2013 to 2026
$3.8M
MtDNA variant modifiers of cardiopulmonary responsiveness to physical activityR01HL121023 · NHLBI · UNIVERSITY OF FLORIDA · PI FRAGOSO, CARLOS A. VAZ, MANINI, TODD · 2014 to 2017
$1.3M
NCATS NIH HHS UL1 TR001412NHLBI NIH HHS HHSN268201100001INHLBI NIH HHS HHSN268201100002INHLBI NIH HHS HHSN268201100004INHLBI NIH HHS HHSN268201100046CNHLBI NIH HHS HHSN268201300007CNHLBI NIH HHS R01 HL105065NHLBI NIH HHS R01 HL121023NIAMS NIH HHS T32 AR064194NIA NIH HHS HHSN271201100004CNIA NIH HHS P30 AG028740WHI NIH HHS HHSN268201100001CWHI NIH HHS HHSN268201100002CWHI NIH HHS HHSN268201100003CWHI NIH HHS HHSN268201100004C
6 · The paper itself

Abstract

Few studies have assessed the association of sedentary time with leukocyte telomere length (LTL). In a cross-sectional study conducted in 2012-2013, we examined associations of accelerometer-measured and self-reported sedentary time with LTL in a sample of 1,481 older white and African-American women from the Women's Health Initiative and determined whether associations varied by level of moderate- to vigorous-intensity physical activity (MVPA). The association between sedentary time and LTL was evaluated using multiple linear regression models. Women were aged 79.2 (standard deviation, 6.7) years, on average. Self-reported sedentary time was not associated with LTL. In a model adjusting for demographic characteristics, lifestyle behaviors, and health-related factors, among women at or below the median level of accelerometer-measured MVPA, those in the highest quartile of accelerometer-measured sedentary time had significantly shorter LTL than those in the lowest quartile, with an average difference of 170 base pairs (95% confidence interval: 4, 340). Accelerometer-measured sedentary time was not associated with LTL in women above the median level of MVPA. Findings suggest that, on the basis of accelerometer measurements, higher sedentary time may be associated with shorter LTL among less physically active women.

Indexed as

Sedentary BehaviorAccelerometryAgedAged, 80 and overBlack or African AmericanCross-Sectional StudiesExerciseFemaleHumansLeukocytesMiddle AgedSelf ReportTelomereWhite Peopleaccelerometryleukocyte telomere lengthmoderate- to vigorous-intensity physical activitysedentary timetelomeres

Identifiers

PMID28100466
PMCPMC5391715
OpenAlexW2574453925

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.