ArticleBMC complementary and alternative medicine2017
Radical Scavenging Activities of Lagerstroemia speciosa (L.) Pers. Petal Extracts and its hepato-protection in CCl
Article in BMC complementary and alternative medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 45 citations in OpenAlex.
- Lagerstroemia Speciosa (L.) Pers mitigates acetaminophen-induced acute liver toxicity in rats through modulations of oxidative stress, inflammation, apoptosis and the NF-κB/TNF-α/iNOS, Nrf2/HO-1, signaling pathways.Journal of molecular histology · 2025Article
- Mini review of plant products as food supplement against MSG-induced liver injury: antioxidant, oxidative stress and histological prospects.Frontiers in pharmacology · 2025Review
- Phenolic Compounds and Antioxidant Capacity Comparison of Wild-Type and Yellow-LeafPlants (Basel, Switzerland) · 2024Article
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- Improved antioxidant activities of spice require enrichment of distinct yet closely-related metabolic pathways.Heliyon · 2023Article
- Chemically DefinedAntioxidants (Basel, Switzerland) · 2023Article
- Comprehensive Analysis of Antioxidant and Hepatoprotective Properties ofAntioxidants (Basel, Switzerland) · 2023Article
- A comprehensive multi-directional exploration of phytochemicals and bioactivities of flower extracts fromBiochemistry and biophysics reports · 2020Article
- Assessment of Antioxidant and Cytotoxic Activities of Extracts ofBiomolecules · 2019Article
- Antioxidant Activity ofAntioxidants (Basel, Switzerland) · 2019Article
- Investigation of biological activities of the flowers of Lagerstroemia speciosa, the Jarul flower of Bangladesh.BMC complementary and alternative medicine · 2018Article
- Hepatoprotective effect of Lobelia alsinoides Lam. in Wistar rats.Journal of Ayurveda and integrative medicineArticle
- Antibiofilm and Quorum Sensing Inhibition (QSI) Potential ofDose-response : a publication of International Hormesis SocietyArticle
- Pharmacodynamic evaluation of self micro-emulsifying formulation of standardized extract of Lagerstroemia speciosa for antidiabetic activity.Journal of Ayurveda and integrative medicineArticle
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLagerstroemia speciosa (L.) Pers. has medicinal importance. Bioactive phytochemicals isolated from different parts of L. speciosa, have revealed hypoglycemic, antibacterial, anti-inflammatory, antioxidant and hepato protective properties. Despite one report from Philippines detailing the use of L. speciosa as curative for fever and as well as diuretic, there is no experimental evidence about the hepatoprotective activity of the flower extracts.
methodsSeveral spectroscopic methods, including GC-MS, were used to characterize phytochemicals present in the petal extract of L. speciosa. Ethanol extract of petals was evaluated for anti-oxidant and free radical scavenging properties by using methods related to hydrogen atom transfer, single electron transfer, reducing power, and metal chelation. This study has also revealed the in vitro antioxidant and in vivo hepatoprotective properties of petal extract against carbon tetra chloride (CCl
resultGCMS of the extract has revealed the presence of several potential antioxidant compounds, of them γ-Sitosterol and 1,2,3-Benzenetriol (Pyrogallol) were the predominant ones. The antioxidants activities of the flower-extract were significantly higher than curcumin (in terms of Nitric oxide scavenging activity; p = 0.0028) or ascorbic acid (in terms of 2,2-Diphenyl-1-Picrylhydrazyl (DPPH) assay; p = 0.0022). The damage control by the flower extract can be attributed to the reduction in lipid peroxidation and restoration of catalase activity. In vitro cytotoxicity tests have shown that the flower extract did not affect growth and survivability of the cell lines. It left beyond doubt that a flower of L. speciosa is a reservoir of antioxidant and hepatoprotective agents capable of reversing the damage inflicted by CCl
conclusionResults from the present study may be used in developing a potential hepato-protective health drink enriched with antioxidants from Lagerstroemia speciosa (L.) Pers.
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