ArticleBMC urology2017
Preoperative lipiodol marking and its role on survival and complication rates of CT-guided cryoablation for small renal masses.
Article in BMC urology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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11 citing papers in PubMed, 29 citations in OpenAlex.
- Percutaneous thermal ablation for renal cell carcinoma: a comprehensive review of current evidence and future directions.La Radiologia medica · 2026Review
- Adjunctive Techniques for Optimizing Percutaneous CT-Guided Cryoablation of Renal Tumours.Cancers · 2026Review
- Combining Transarterial Embolization and Percutaneous Cryoablation for Early-Stage Renal Cell Carcinoma: Embolization Materials and Impacts of Tumor Size.Tomography (Ann Arbor, Mich.) · 2024Article
- Computed Tomography-guided Puncture: Preprocedural Preparation, Technical Tips, and Radioprotection.Interventional radiology (Higashimatsuyama-shi (Japan) · 2024Review
- Effects of percutaneous cryoablation for renal tumor on overall and split renal function.Japanese journal of radiology · 2024Article
- Depiction rate of feeding arteries of renal cell carcinoma on four-dimensional computed tomography angiography.Japanese journal of radiology · 2024Article
- Preoperative Tyrosine Kinase Inhibitors Before Percutaneous Cryoablation for Clinical T1b Renal Tumors.Cureus · 2024Article
- Effect of lipiodol marking before CT-guided cryoablation on the outcome of sporadic renal cell carcinoma.Diagnostic and interventional radiology (Ankara, Turkey) · 2024Article
- Diagnostic accuracy of percutaneous core biopsy before cryoablation for small-sized renal cell carcinoma.Diagnostic and interventional radiology (Ankara, Turkey) · 2023Article
- Renal cryoablation combined with prior transcatheter arterial embolization in non-dialysis patients with stage 4 or 5 chronic kidney disease: a retrospective study.Japanese journal of radiology · 2023Article
- Recent progress in cryoablation cancer therapy and nanoparticles mediated cryoablation.Theranostics · 2022Review
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Authors and funding
11 authors at 1 institution in 1 country.
Funding
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Abstract
backgroundPartial nephrectomy for small renal masses (SRM) may be useful for preserving renal function, but is technically more difficult than radical nephrectomy. Cryoablation may be performed under local anesthesia. The objective of the present study is to assess the safety and therapeutic efficacy of cryoablation with lipiodol marking for SRM.
methodsCryoablation therapy was performed on 42 patients under local anesthesia. Their median age was 74 years (31-91). The median tumor diameter was 21 mm (10-42). Responses to the treatment were evaluated using modified Response Evaluation Criteria in Solid Tumors (mRECIST) by contrast-enhanced CT. In six patients (14.3%) for whom it was not possible to use contrast medium, plain CT findings were assessed according to Response Evaluation Criteria in Solid Tumors (RECIST).
resultsTwenty-nine (69%) and five (12%) patients achieved complete responses (CR) and partial responses (PR), respectively, while four (10%) and four (10%) patients each had stable disease (SD) and progressive disease (PD) after the first course of therapy. A second course of cryoablation therapy with lipiodol marking was performed on three out of four patients with PD after the first course of therapy, and resulted in a total of 32 patients achieving CR (76%). Four (36.4%) out of 11 patients for whom lipiodol marking was not conducted had PD, whereas none of the 31 patients for whom lipiodol marking was conducted had PD. All grade complications were reported in 11 (24.4%) patients while grade 3 in two (4.4%) patients. 11 (24.4%) A significant difference was observed in postoperative hemorrhagic events in all grades (18% in patients undergoing cryoablation without lipiodol marking vs. 0% in patients undergoing cryoablation without lipiodol marking).
conclusionsAlthough further studies involving more patients are needed in order to evaluate long-term results, cryoablation therapy appears to be a useful treatment option for SRM. Preoperative marking with lipiodol was helpful for improving complication and survival rates with cryoablation.
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