ArticleBMC infectious diseases2017
Exploring surface cleaning strategies in hospital to prevent contact transmission of methicillin-resistant Staphylococcus aureus.
Article in BMC infectious diseases, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 3 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 3 syntheses or guidelines pooled it, 46 citations in OpenAlex.
- Role of pulsed-xenon ultraviolet light in reducing healthcare-associated infections: a systematic review and meta-analysis.Epidemiology and infection · 2020Pooled it
- Simulation models for transmission of health care-associated infection: A systematic review.American journal of infection control · 2020Pooled it
- A systematic review of transmission dynamic studies of methicillin-resistant Staphylococcus aureus in non-hospital residential facilities.BMC infectious diseases · 2018Pooled it
- Antimicrobial surface coating in the emergency department as protective technology for infection control (ASEPTIC): a pilot randomized controlled trial.Antimicrobial resistance and infection control · 2024Trial
- Public surface disinfection every 2 hours can reduce the infection risk of norovirus in airports up to 83.PLoS computational biology · 2024Article
- Bacteriophages in Infectious Diseases and Beyond-A Narrative Review.Antibiotics (Basel, Switzerland) · 2023Review
- Increasing contributions of airborne route in SARS-CoV-2 omicron variant transmission compared with the ancestral strain.Building and environment · 2022Article
- Inanimate Surfaces as a Source of Hospital Infections Caused by Fungi, Bacteria and Viruses with Particular Emphasis on SARS-CoV-2.International journal of environmental research and public health · 2022Review
- Transparent Anti-SARS-CoV-2 and Antibacterial Silver Oxide Coatings.ACS applied materials & interfaces · 2022Article
- Bacteria Associated with Healthcare-Associated Infections on Environmental Samples Obtained from Two Fire Departments.International journal of environmental research and public health · 2021Article
- Comparing approaches for modelling indirect contact transmission of infectious diseases.Journal of the Royal Society, Interface · 2021Article
- The alarming association between antibiotic resistance and reduced susceptibility to biocides in nosocomial MRSA isolates from two regional hospitals in Egypt.Archives of microbiology · 2021Article
- Antibacterial Treatment of Selected High-Touch Objects and Surfaces within Provision of Nursing Care in Terms of Prevention of Healthcare-Associated Infections.Healthcare (Basel, Switzerland) · 2021Article
- Review
- Disinfection of methicillin-resistantAccess microbiology · 2021Article
- One Health in hospitals: how understanding the dynamics of people, animals, and the hospital built-environment can be used to better inform interventions for antimicrobial-resistant gram-positive infections.Antimicrobial resistance and infection control · 2020Review
- Quantifying the relative impact of contact heterogeneity on MRSA transmission in ICUs - a modelling study.BMC infectious diseases · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCleaning of environmental surfaces in hospitals is important for the control of methicillin-resistant Staphylococcus aureus (MRSA) and other hospital-acquired infections transmitted by the contact route. Guidance regarding the best approaches for cleaning, however, is limited.
methodsIn this study, a mathematical model based on ordinary differential equations was constructed to study MRSA concentration dynamics on high-touch and low-touch surfaces, and on the hands and noses of two patients (in two hospitals rooms) and a health care worker in a hypothetical hospital environment. Two cleaning interventions - whole room cleaning and wipe cleaning of touched surfaces - were considered. The performance of the cleaning interventions was indicated by a reduction in MRSA on the nose of a susceptible patient, relative to no intervention.
resultsWhole room cleaning just before first patient care activities of the day was more effective than whole room cleaning at other times, but even with 100% efficiency, whole room cleaning only reduced the number of MRSA transmitted to the susceptible patient by 54%. Frequent wipe cleaning of touched surfaces was shown to be more effective that whole room cleaning because surfaces are rapidly re-contaminated with MRSA after cleaning. Wipe cleaning high-touch surfaces was more effective than wipe cleaning low-touch surfaces for the same frequency of cleaning. For low wipe cleaning frequency (≤3 times per hour), high-touch surfaces should be targeted, but for high wipe cleaning frequency (>3 times per hour), cleaning should target high- and low-touch surfaces in proportion to the surface touch frequency. This study reproduces the observations from a field study of room cleaning, which provides support for the validity of our findings.
conclusionsDaily whole room cleaning, even with 100% cleaning efficiency, provides limited reduction in the number of MRSA transmitted to susceptible patients via the contact route; and should be supplemented with frequent targeted cleaning of high-touch surfaces, such as by a wipe or cloth containing disinfectant.
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