Evidence map›Paper›PMID 28099851›Full record

ArticleCell reports2017

A Molecular and Cellular Context-Dependent Role for Ir76b in Detection of Amino Acid Taste.

Anindya Ganguly, Lisa Pang, Vi-Khoi Duong, Angelina Lee, Hanni Schoniger, Erika Varady, Anupama Dahanukar

Abstract read
In one paragraph

Article in Cell reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 104 papers.

0numbers the graph read from it
0cells of the map it votes in
104citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

104 citing papers in PubMed.

  1. Article
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  4. Review
  5. Article
  6. Comparative Antennal Transcriptome Analysis ofInternational journal of molecular sciences · 2025
    Article
  7. Article
  8. Article
  9. Article
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  14. Genome-Wide Identification and Evolutionary Analysis ofAnimals : an open access journal from MDPI · 2025
    Article
  15. Article
  16. Article
  17. Review
  18. Review
  19. Article
  20. Article

44 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Anindya GangulyInterdepartmental Neuroscience Program, University of California, Riverside, CA 92521, USA.
Lisa PangDepartment of Entomology, University of California, Riverside, CA 92521, USA.
Vi-Khoi DuongUniversity Honors Program, University of California, Riverside, CA 92521, USA.
Angelina LeeUndergraduate Anthropology Major, University of California, Riverside, CA 92521, USA.
Hanni SchonigerUniversity Honors Program, University of California, Riverside, CA 92521, USA.
Erika VaradyUniversity Honors Program, University of California, Riverside, CA 92521, USA.
Anupama DahanukarInterdepartmental Neuroscience Program, University of California, Riverside, CA 92521, USA; Department of Entomology, University of California, Riverside, CA 92521, USA. Electronic address: anupama.dahanukar@ucr.edu.

Funding

Resource Component: Acquisition, maintenance and distribution of Drosophila stocksP40OD018537 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI Annette L. Parks · 2014 to 2026
$13.5M
Receptors and Neurons Mediating Acid Taste in DrosophilaR21DC012408 · NIDCD · UNIVERSITY OF CALIFORNIA RIVERSIDE · PI DAHANUKAR, ANUPAMA ARUN · 2012 to 2013
$394k
NIDCD NIH HHS R21 DC012408NIH HHS P40 OD018537
6 · The paper itself

Abstract

Amino acid taste is expected to be a universal property among animals. Although sweet, bitter, salt, and water tastes have been well characterized in insects, the mechanisms underlying amino acid taste remain elusive. From a Drosophila RNAi screen, we identify an ionotropic receptor, Ir76b, as necessary for yeast preference. Using calcium imaging, we identify Ir76b

Indexed as

Amino AcidsAnimalsAnimals, Genetically ModifiedBase SequenceBehavior, AnimalCalciumCRISPR-Cas SystemsDrosophila melanogasterDrosophila ProteinsFemaleMaleMicroscopy, ConfocalNeuronsPhenotypeReceptors, Ionotropic GlutamateRNA InterferenceAmino AcidsCalciumDrosophila ProteinsIR76b protein, DrosophilaReceptors, Ionotropic GlutamateSodium ChannelsSodium ChlorideSugarsamino acid tasteDrosophilafeeding behaviorionotropic receptorsIr76bpost-mating behavior

Identifiers

PMID28099851
PMCPMC5258133

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.