Evidence map›Paper›PMID 28099850›Full record

ArticleCell reports2017

Synaptotagmin 2 Is the Fast Ca

Chong Chen, Itaru Arai, Rachel Satterfield, Samuel M Young, Peter Jonas

Open access · goldAbstract read
In one paragraph

Article in Cell reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 80 citations in OpenAlex.

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  16. Deconstructing Synaptotagmin-1's Distinct Roles in Synaptic Vesicle Priming and Neurotransmitter Release.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Chong ChenIST Austria (Institute of Science and Technology Austria), Am Campus 1, 3400 Klosterneuburg, Austria.
Itaru AraiIST Austria (Institute of Science and Technology Austria), Am Campus 1, 3400 Klosterneuburg, Austria.
Rachel SatterfieldMax Planck Florida Institute for Neuroscience, Research Group Molecular Mechanisms of Synaptic Function, Jupiter, FL 33458, USA.
Samuel M YoungMax Planck Florida Institute for Neuroscience, Research Group Molecular Mechanisms of Synaptic Function, Jupiter, FL 33458, USA.
Peter JonasIST Austria (Institute of Science and Technology Austria), Am Campus 1, 3400 Klosterneuburg, Austria. Electronic address: peter.jonas@ist.ac.at.
Institute of Science and Technology Austria · ATMax Planck Florida Institute for Neuroscience · US

Funding

Regulation of Synaptic Vesicle Dynamics in the Auditory SystemR01DC014093 · NIDCD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI YOUNG, SAMUEL MATTHEW · 2015 to 2024
$3.7M
Austrian Science Fund FWF P 24909European Research Council 268548NIDCD NIH HHS R01 DC014093
6 · The paper itself

Abstract

GABAergic synapses in brain circuits generate inhibitory output signals with submillisecond latency and temporal precision. Whether the molecular identity of the release sensor contributes to these signaling properties remains unclear. Here, we examined the Ca

Indexed as

AdenoviridaeAnimalsCalciumCerebellumEvoked PotentialsGenetic VectorsIn Vitro TechniquesMiceMice, Inbred C57BLMice, KnockoutMicroscopy, FluorescencePhosphinic AcidsPurkinje CellsPyridinesSynapsesSynaptic Transmission(1,2,5,6-tetrahydropyridin-4-yl)methylphosphinic acidCalciumPhosphinic AcidsPyridinesSynaptotagmin ISynaptotagmin IIbasket cellsCa(2+) sensorcerebellumendocytosisexocytosisfeedforward inhibitionGABAergic synapsespool replenishmentsynaptotagmintransmitter release

Identifiers

PMID28099850
PMCPMC5276807
OpenAlexW2574480161

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.