Evidence map›Paper›PMID 28099744›Full record

Observational studyInternational journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics2017

A retrospective cohort study of hemostatic agent use during hysterectomy and risk of post-operative complications.

John A Harris, Shitanshu Uppal, Neil Kamdar, Carolyn W Swenson, Darrell Campbell, Daniel M Morgan

Abstract readMulticenter StudyObservational Study
In one paragraph

Observational study in International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. The use of sealing hemostat patch (HEMOPATCHArchives of gynecology and obstetrics · 2023
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

John A HarrisDivision of Women's Health, Department of Obstetrics and Gynecology, University of Michigan, Ann Arbor, MI, USA.
Shitanshu UppalDivision of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of Michigan, Ann Arbor, MI, USA.
Neil KamdarDepartment of Obstetrics and Gynecology, University of Michigan, Ann Arbor, MI, USA.
Carolyn W SwensonDivision of Urogynecology, Department of Obstetrics and Gynecology, University of Michigan, Ann Arbor, MI, USA.
Darrell CampbellDepartment of Surgery, University of Michigan, Ann Arbor, MI, USA.
Daniel M MorganDivision of Urogynecology, Department of Obstetrics and Gynecology, University of Michigan, Ann Arbor, MI, USA.

Funding

Magee-Womens Basic and Translational Reproductive Health Training ProgramK12HD063087 · NICHD · MAGEE-WOMEN'S RES INST AND FOUNDATION · PI EDWARDS, ROBERT PAGE · 2009 to 2019
$3.7M
University of Michigan WRHR Career Development ProgramK12HD065257 · NICHD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI FENNER, DEE ELLEN · 2010 to 2019
$3.4M
NICHD NIH HHS K12 HD063087NICHD NIH HHS K12 HD065257
6 · The paper itself

Abstract

objectiveTo determine if the use of intraoperative hemostatic agents was a risk factor for post-operative adverse events within 30 days of patients undergoing hysterectomy.

methodA population-based retrospective cohort study included data from patients undergoing hysterectomy for any indication between January 1, 2013, and December 31, 2014, at 52 hospitals in Michigan, USA. Any individuals with missing covariate data were excluded, and multivariable logistic regression and propensity score-matching were used to estimate the rate of post-operative adverse events associated with intra-operative hemostatic agents independent of demographic and surgical factors.

resultsThere were 17 960 surgical procedures included in the analysis, with 4659 (25.9%) that included the use of hemostatic agents. Hemostatic agent use was associated with an increase in predicted hospital re-admissions (P=0.007). Among all hysterectomy approaches, and after adjusting for demographic and surgical factors, hemostatic agent use during robotic-assisted laparoscopic hysterectomy was associated with an increased predicted rate of blood transfusions (P=0.019), an increased predicted rate of pelvic abscess diagnoses (P=0.001), an increased predicted rate of hospital re-admission (P=0.001), and an increased predicted rate of re-operation (P=0.021).

conclusionHemostatic agents should be used carefully owing to associations with increased post-operative re-admissions and re-operations when used during hysterectomy.

Indexed as

AdultBlood TransfusionFemaleHemostaticsHumansHysterectomyLaparoscopyLogistic ModelsMichiganMiddle AgedMultivariate AnalysisPatient AdmissionPelvic InfectionPostoperative ComplicationsReoperationRetrospective StudiesHemostaticsBlood transfusionsComplicationsHemostatic agentsHospital readmissionsHysterectomyPelvic abscessPropensity score matching

Identifiers

PMID28099744
PMCPMC5245183

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.