Evidence map›Paper›PMID 28099657›Full record

SynthesisRevista de saude publica2016

Quality of life and treatment adherence in hypertensive patients: systematic review with meta-analysis.

Ana Célia Caetano de Souza, José Wicto Pereira Borges, Thereza Maria Magalhães Moreira

Open access · goldAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Revista de saude publica, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 89 citations in OpenAlex.

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  11. A bibliometric analysis and mapping of global research trends in antihypertensive medication adherence (1975-2024).The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2025
    Review
  12. The Role of Social Functioning Between Vitality and Mental Distress in Hypertension: A Partial Mediation Model.European journal of investigation in health, psychology and education · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Ana Célia Caetano de SouzaUnidade de Farmacologia Clínica. Núcleo de Pesquisa e Desenvolvimento de Medicamentos. Universidade Federal do Ceará. Fortaleza, CE, Brasil.
José Wicto Pereira BorgesPrograma de Graduação em Enfermagem. Programa de Pós-Graduação em Saúde e Comunidade. Campus Amilcar Ferreira Sobral. Universidade Federal do Piauí. Floriano, PI, Brasil.
Thereza Maria Magalhães MoreiraPrograma de Pós-Graduação em Saúde Coletiva. Programa de Pós-Graduação em Cuidados Clínicos em Enfermagem e Saúde. Centro de Ciências da Saúde. Universidade Estadual do Ceará. Fortaleza, CE, Brasil.
Universidade Estadual do Ceará · BRUniversidade Federal do Ceará · BRUniversidade Federal do Piauí · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo verify the effects of antihypertensive treatment (pharmacological and non-pharmacological) on the health-related quality of life of individuals with hypertension.

methodsWe conducted a systematic review with meta-analysis using the following databases: IBECS, LILACS, SciELO, Medline, Cochrane, Science Direct, Scopus and the Brazilian Capes Theses and Dissertations Database. The statistical analysis was performed using Review Manager, version 5.2. The average difference was used for the summarization of meta-analytic effect by the fixed-effect model. Twenty studies were included.

resultsThe summarization of the effect showed an average increase of 2.45 points (95%CI 1.02-3.87; p < 0.0008) in the quality of life of individuals adhering to non-pharmacological treatment for arterial hypertension. Adherence to pharmacological treatment indicated an average increase of 9.24 points (95%CI 8.16-10.33; p < 0.00001) in the quality of life of individuals with arterial hypertension.

conclusionsNon-pharmacological treatment improves the overall quality of life and physical domain of people with arterial hypertension. Adherence to pharmacological treatment has a positive impact on the mental and physical domains of patients, as it did on the overall quality of life score. OBJETIVO: Verificar os efeitos do tratamento anti-hipertensivo (farmacológico e não-farmacológico) na qualidade de vida relacionada à saúde de pessoas com hipertensão arterial. MÉTODOS: Foi conduzida revisão sistemática com metanálise utilizando as bases de dados IBECS, Lilacs, SciELO, Medline, Cochrane, Science Direct, Scopus e o banco de teses da Capes. A análise estatística foi realizada pelo Review Manager versão 5.2. Foi utilizada a diferença da média na sumarização do efeito metanalítico pelo modelo de efeito fixo. Vinte estudos foram incluídos. RESULTADOS: A sumarização do efeito mostrou incremento de 2,45 pontos na média (IC95% 1,02-3,87; p < 0,0008) da qualidade de vida em pessoas com adesão ao tratamento não farmacológico para hipertensão arterial. A adesão ao tratamento farmacológico indicou aumento de 9,24 pontos na média (IC95% 8,16-10,33; p < 0,00001) da qualidade de vida em pessoas com hipertensão arterial. CONCLUSÕES: O tratamento não-farmacológico melhora a qualidade de vida global e o domínio físico de pessoas com hipertensão arterial. A adesão ao tratamento farmacológico impacta positivamente nos domínios mental, físico e escore total da qualidade de vida.

Indexed as

Quality of LifeAntihypertensive AgentsBrazilHumansHypertensionMedication AdherencePatient ComplianceAntihypertensive Agents

Identifiers

PMID28099657
PMCPMC5152803
OpenAlexW2566693518

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.