Evidence map›Paper›PMID 28099316›Full record

ArticleRetina (Philadelphia, Pa.)2017

PNEUMATIC VITREOLYSIS FOR RELIEF OF VITREOMACULAR TRACTION.

Clement K Chan, Jason N Crosson, Calvin E Mein, Noha Daher

Registry-linked trialOpen access · hybridAbstract readCase Reports
In one paragraph

Article in Retina (Philadelphia, Pa.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03945695 (Pneumatic Vitreolysis Using the Drinking Bird Technique for Management of Vitreomacular Traction. A Prospective, Non-randomized, Interventional Study.), which is not on this map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03945695 naterminatednot on this mapstarted 2018, after this paper: background citation

Pneumatic Vitreolysis Using the Drinking Bird Technique for Management of Vitreomacular Traction. A Prospective, Non-randomized, Interventional Study.

TypeinterventionalSponsorUniversity of Split, School of MedicineRan2018 to 2020Enrolled12ConditionsVitreomacular Traction SyndromeArmsPneumatic Vitreolysis in combination with "Drinking-Bird-Technique"
3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. [Microstructural retinal changes after pharmacological vitreolysis with ocriplasmin-an SD-OCT supported analysis].Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft · 2020
    Article
  8. Review of Vitreopapillary Traction Syndrome.Neuro-ophthalmology (Aeolus Press) · 2020
    Review
  9. Article
  10. Loculated subretinal fluid after pneumatic vitreolysis.American journal of ophthalmology case reports · 2019
    Article
  11. Focal vitreomacular traction: Resolution after ocular massage.American journal of ophthalmology case reports · 2019
    Article
  12. Article
  13. Comparison of the horizontal diameter to a modeled area of traction in eyes with vitreomacular traction: is the diameter close enough to the truth?Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2018
    Article
  14. Effect of intravitreal CSpektrum der Augenheilkunde : Zeitschrift der Osterreichischen Ophthalmologischen Gesellschaft, OOG · 2018
    Article
  15. Ocriplasmin treatment for vitreomacular traction in real life: can the indication spectrum be expanded?Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2017
    Article
  16. Review
  17. Article
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  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Clement K Chan*Southern California Desert Retina Consultants, Palm Desert, California; †Department of Ophthalmology, Loma Linda University, Loma Linda, California; ‡Retina Consultants of Alabama, The University of Alabama at Birmingham, Birmingham, Alabama; §Retinal Consultants of San Antonio, San Antonio, Texas; and ¶Department of Allied Health Studies, School of Allied Health Professions, Loma Linda University, Loma Linda California.
Jason N Crosson
Calvin E Mein
Noha Daher
Retina Consultants of Houston · USLoma Linda University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the outcome of perfluoropropane (C3F8) gas injection for symptomatic vitreomacular traction (VMT) with or without Stage 2 macular hole (MH).

methodsA retrospective review of eyes with VMT treated with 0.3 mL of C3F8 gas was performed. Patients avoided the supine position until gas resolution. Patients with small MH maintained partial face-down positioning.

resultsForty-nine consecutive patients (50 eyes) with symptomatic VMT underwent pneumatic vitreolysis between 2010 and 2016. A posterior vitreous detachment developed in 43 eyes (86.0%) after a single gas injection, at a median of 3.0 weeks. Twenty-eight of 35 eyes (80.0%) with VMT only and all 15 eyes (100%) with a small Stage 2 MH developed a posterior vitreous detachment, with MH closure in 10 of 15 eyes (66.7%). Median baseline and last best spectacle-corrected visual acuities were 20/50 and 20/40, respectively (P < 0.001). Mean follow-up time was 11.1 ± 9.9 months. Rate of posterior vitreous detachment was reduced with presence of diabetes mellitus (25%) and with thick cellophane membrane (50%). Univariate analysis showed increased VMT release for eyes with VMT extent within 1 disk area (χ = 13.1, P = 0.002), eyes with absence of diabetes mellitus (χ = 8.8, P = 0.007), and eyes with Stage 2 MH (χ = 5.47, P = 0.019); there was a trend between success and lack of thick cellophane membrane (χ = 3.32, P = 0.068). Results using logistic regression also showed younger age (P = 0.012), followed by better baseline best spectacle-corrected visual acuity (P = 0.044), lack of diabetes mellitus (P = 0.077), and female gender (P = 0.045) to be predictors of increased VMT release. One VMT-only eye formed a MH and another VMT-only eye developed a retinal detachment. Both eyes responded to vitrectomy.

conclusionPneumatic vitreolysis with limited face-down position is a viable option for treating VMT with few adverse events. More studies are needed to elucidate its indications, benefits, and risks.

Indexed as

Postoperative ComplicationsAgedDisease ProgressionEndotamponadeFemaleFluorocarbonsHumansMalePatient PositioningRetinal DiseasesRetinal PerforationsRetrospective StudiesTomography, Optical CoherenceVitreoretinal SurgeryVitreous BodyVitreous DetachmentFluorocarbonsperflutren

Identifiers

PMID28099316
PMCPMC5642323
OpenAlexW2575752886

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.