Evidence map›Paper›PMID 28099113›Full record

ArticleeLife2017

RAGE deficiency predisposes mice to virus-induced paucigranulocytic asthma.

Jaisy Arikkatt, Md Ashik Ullah, Kirsty Renfree Short, Vivan Zhang, Wan Jun Gan, Zhixuan Loh, Rhiannon B Werder, Jennifer Simpson, Peter D Sly, Stuart B Mazzone and 5 more

Open access · goldAbstract read
In one paragraph

Article in eLife, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.2field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Breathing new life into the study of COPD with genes identified from genome-wide association studies.European respiratory review : an official journal of the European Respiratory Society · 2024
    Review
  3. Article
  4. Review
  5. Review
  6. Review
  7. Article
  8. Article
  9. Targeting the P2YAmerican journal of respiratory and critical care medicine · 2022
    Article
  10. Article
  11. Review
  12. Modulation of Vagal Sensory NeuronsFrontiers in physiology · 2021
    Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 6 institutions in 1 country.

Jaisy ArikkattSchool of Biomedical Science, University of Queensland, Brisbane, Australia.
Md Ashik UllahSchool of Biomedical Science, University of Queensland, Brisbane, Australia.
Kirsty Renfree ShortSchool of Biomedical Science, University of Queensland, Brisbane, Australia.
Vivan ZhangSchool of Biomedical Science, University of Queensland, Brisbane, Australia.
Wan Jun GanSchool of Biomedical Science, University of Queensland, Brisbane, Australia.
Zhixuan LohSchool of Biomedical Science, University of Queensland, Brisbane, Australia.
Rhiannon B WerderSchool of Biomedical Science, University of Queensland, Brisbane, Australia.
Jennifer SimpsonSchool of Biomedical Science, University of Queensland, Brisbane, Australia.
Peter D SlyAustralian Infectious Diseases Research Centre, The University of Queensland, Brisbane, Australia.
Stuart B MazzoneSchool of Biomedical Science, University of Queensland, Brisbane, Australia.
Kirsten M SpannAustralian Infectious Diseases Research Centre, The University of Queensland, Brisbane, Australia.
Manuel Ar FerreiraQIMR Berghofer Medical Research Institute, Brisbane, Australia.
John W UphamAustralian Infectious Diseases Research Centre, The University of Queensland, Brisbane, Australia.
Maria B SukkarWoolcock Institute of Medical Research, Sydney Medical School, University of Sydney, New South Wales, Australia.
Simon PhippsSchool of Biomedical Science, University of Queensland, Brisbane, Australia.ORCID 0000-0002-7388-3612
The University of Queensland · AUChildren's Medical Research Institute · AUQIMR Berghofer Medical Research Institute · AUQueensland University of Technology · AUThe University of Sydney · AUUniversity of Technology Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Asthma is a chronic inflammatory disease. Although many patients with asthma develop type-2 dominated eosinophilic inflammation, a number of individuals develop paucigranulocytic asthma, which occurs in the absence of eosinophilia or neutrophilia. The aetiology of paucigranulocytic asthma is unknown. However, both respiratory syncytial virus (RSV) infection and mutations in the receptor for advanced glycation endproducts (

Indexed as

Genetic Predisposition to DiseaseAgranulocytosisAnimalsAsthmaHMGB1 ProteinMiceMurine pneumonia virusReceptor for Advanced Glycation End ProductsViral LoadAger protein, mouseHMGB1 ProteinHMGB1 protein, mouseReceptor for Advanced Glycation End ProductsasthmaHMGB1immunologyinfectious diseasemicrobiologymousepaucigranulocyticRAGEvirus infection

Identifiers

PMID28099113
PMCPMC5243115
OpenAlexW2574654815

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.