Evidence map›Paper›PMID 28098999›Full record

ArticleJournal of the American Chemical Society2017

DNA Deformation-Coupled Recognition of 8-Oxoguanine: Conformational Kinetic Gating in Human DNA Glycosylase.

Haoquan Li, Anton V Endutkin, Christina Bergonzo, Lin Fu, Arthur Grollman, Dmitry O Zharkov, Carlos Simmerling

Open access · greenAbstract read
In one paragraph

Article in Journal of the American Chemical Society, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Inhibitors of DNA Glycosylases as Prospective Drugs.International journal of molecular sciences · 2020
    Review
  9. Fast Implementation of the Nudged Elastic Band Method in AMBER.Journal of chemical theory and computation · 2019
    Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Haoquan Li
Anton V EndutkinNovosibirsk State University , 2 Pirogova Street, Novosibirsk 630090, Russia.
Christina Bergonzo
Lin FuSchool of Pharmaceutical Sciences, Wenzhou Medical University , Wenzhou 325035, P. R. China.
Arthur Grollman
Dmitry O ZharkovNovosibirsk State University , 2 Pirogova Street, Novosibirsk 630090, Russia.
Carlos SimmerlingORCID 0000-0002-7252-4730
Novosibirsk State University · RUWenzhou Medical University · CN

Funding

POTENTIAL ANTIVIRAL AGENTS--TRIPHENYLMETHANE DYESR01CA017395 · NCI · STATE UNIVERSITY NEW YORK STONY BROOK · PI GROLLMAN, ARTHUR PATRICK · 1985 to 2012
$4.1M
New Solvent Models, Sampling Methods and Maintenance of Amber SoftwareR01GM107104 · NIGMS · STATE UNIVERSITY NEW YORK STONY BROOK · PI SIMMERLING, CARLOS · 2013 to 2020
$2.4M
NCI NIH HHS R01 CA017395NIGMS NIH HHS R01 GM107104
6 · The paper itself

Abstract

8-Oxoguanine (8-oxoG), a mutagenic DNA lesion generated under oxidative stress, differs from its precursor guanine by only two substitutions (O

Indexed as

DNA GlycosylasesMolecular Dynamics SimulationCatalytic DomainCrystallography, X-RayDNAGuanineHumansKineticsMolecular ConformationMolecular Structure8-hydroxyguanineDNADNA GlycosylasesGuanine

Identifiers

PMID28098999
PMCPMC5321822
OpenAlexW2573523681

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.