Evidence map›Paper›PMID 28098996›Full record

ArticleJournal of natural products2017

Ulapualides C-E Isolated from a Hawaiian Hexabranchus sanguineus Egg Mass.

Stephen M Parrish, Wesley Yoshida, Baojun Yang, Philip G Williams

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of natural products, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Stephen M ParrishDepartment of Chemistry, University of Hawaii at Manoa , Honolulu, Hawaii 96822, United States.
Wesley YoshidaDepartment of Chemistry, University of Hawaii at Manoa , Honolulu, Hawaii 96822, United States.
Baojun YangUniversity of Hawaii Cancer Center , 701 Ilalo Street, Honolulu, Hawaii 96813, United States.
Philip G WilliamsDepartment of Chemistry, University of Hawaii at Manoa , Honolulu, Hawaii 96822, United States.ORCID 0000-0001-8987-0683

Funding

Capture the Inhibitor: Affinity Approaches to the Discovery of Secretase LeadsR01AG039468 · NIA · UNIVERSITY OF HAWAII AT MANOA · PI WILLIAMS, PHILIP · 2011 to 2014
$1.1M
NIA NIH HHS R01 AG039468
6 · The paper itself

Abstract

Three new ulapualides (3-5) were isolated from egg masses of the nudibranch Hexabranchus sanguineus. The structures of 3-5 were deduced by analyses of physical and spectroscopic data in comparisons with ulapualides A (1) and B (2). Ulapualide C demonstrated submicromolar cytotoxicity against select NCI cell lines (768-0, DU-145, MDA-MB-231, and A549) with the most potent activity against MDA-MB-231 cells (IC

Indexed as

AnimalsDrug Screening Assays, AntitumorGastropodaHawaiiHumansMarine BiologyMolecular StructureOvumOxazolesOxazolesulapualide Culapualide Dulapualide E

Identifiers

PMID28098996
PMCPMC5365346

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.