Evidence map›Paper›PMID 28098826›Full record

ArticleMolecules (Basel, Switzerland)2017

Hair Growth Promoting and Anticancer Effects of p21-activated kinase 1 (PAK1) Inhibitors Isolated from Different Parts of Alpinia zerumbet.

Nozomi Taira, Binh Cao Quan Nguyen, Shinkichi Tawata

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
3.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Phytochemicals ofMolecules (Basel, Switzerland) · 2024
    Review
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Nozomi TairaDepartment of Bioscience and Biotechnology, The United Graduate School of Agricultural Sciences, Kagoshima University, Korimoto 1-21-24, Kagoshima 890-8580, Japan. taira5935@gmail.com.
Binh Cao Quan NguyenDepartment of Bioscience and Biotechnology, The United Graduate School of Agricultural Sciences, Kagoshima University, Korimoto 1-21-24, Kagoshima 890-8580, Japan. ncqbinh@gmail.com.
Shinkichi TawataPAK Research Center, University of the Ryukyus, Okinawa 903-0213, Japan. b986097@agr.u-ryukyu.ac.jp.
University of the Ryukyus · JPKagoshima University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PAK1 (p21-activated kinase 1) is an emerging target for the treatment of hair loss (alopecia) and cancer; therefore, the search for PAK1 blockers to treat these PAK1-dependent disorders has received much attention. In this study, we evaluated the anti-alopecia and anticancer effects of PAK1 inhibitors isolated from

Indexed as

AlpiniaAntineoplastic AgentsCell LineCell ProliferationCell SurvivalDiterpenesEpithelial CellsFlowersFuransGene ExpressionGlucuronidesHair FollicleHumansKaempferolsMinoxidilp21-Activated KinasesAntineoplastic AgentsDiterpenesFuransGlucuronideskaempferol-3-O-glucuronideKaempferolsMinoxidilp21-Activated KinasesPAK1 protein, humanProtein Kinase InhibitorsQuinolizinesAlpinia zerumbetcancer">d-glucuronidehair growthkaempferol-3-O-β-PAK1 inhibitors

Identifiers

PMID28098826
PMCPMC6155721
OpenAlexW2575329817

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.