Evidence map›Paper›PMID 28098761›Full record

ReviewInternational journal of molecular sciences2017

Pancreatic Neuroendocrine Neoplasms: Basic Biology, Current Treatment Strategies and Prospects for the Future.

Akihiro Ohmoto, Hirofumi Rokutan, Shinichi Yachida

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 1 pooled it
6.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 1 synthesis or guideline pooled it, 63 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Venous thromboembolism following surgery for pancreatic neuroendocrine neoplasms.Research and practice in thrombosis and haemostasis · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Clinicopathological and genomic features in patients with head and neck neuroendocrine carcinoma.Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc · 2021
    Article
  12. [ELF4 promotes proliferation and inhibits apoptosis of human insulinoma cells by activating Akt signaling].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2021
    Article
  13. Article
  14. Observational
  15. Article
  16. Review
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Akihiro OhmotoDivision of Cancer Genomics, National Cancer Center Research Institute, Tokyo 1040045, Japan. aohmoto@ncc.go.jp.
Hirofumi RokutanDivision of Cancer Genomics, National Cancer Center Research Institute, Tokyo 1040045, Japan. hrokutan@ncc.go.jp.
Shinichi YachidaDivision of Cancer Genomics, National Cancer Center Research Institute, Tokyo 1040045, Japan. syachida@ncc.go.jp.
National Cancer Centre Japan · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pancreatic neuroendocrine neoplasms (pNENs) are rare tumors accounting for only 1%-2% of all pancreatic tumors. pNENs are pathologically heterogeneous and are categorized into three groups (neuroendocrine tumor: NET G1, NET G2; and neuroendocrine carcinoma: NEC) on the basis of the Ki-67 proliferation index and the mitotic count according to the 2010 World Health Organization (WHO) classification of gastroenteropancreatic NENs. NEC in this classification includes both histologically well-differentiated and poorly differentiated subtypes, and modification of the WHO 2010 classification is under discussion based on genetic and clinical data. Genomic analysis has revealed NETs G1/G2 have genetic alterations in chromatin remodeling genes such as

Indexed as

Carcinoma, NeuroendocrineCell DifferentiationHumansModels, BiologicalPancreatic NeoplasmsSignal Transduction2010 WHO classificationeverolimusKi-67 indexmitotic countplatinum regimenpNECpNENssunitinibtumor differentiationwhole-exome sequence data

Identifiers

PMID28098761
PMCPMC5297776
OpenAlexW2561506106

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.