ArticleRetina (Philadelphia, Pa.)2017
ASSESSMENT OF RETINAL BLOOD FLOW IN DIABETIC RETINOPATHY USING DOPPLER FOURIER-DOMAIN OPTICAL COHERENCE TOMOGRAPHY.
Article in Retina (Philadelphia, Pa.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 36 citations in OpenAlex.
- Repeatability and reliability of retinal arterial hemodynamics measurement using Doppler holography.Journal of biomedical optics · 2026Article
- Article
- Inner retinal oxygen delivery and metabolism in progressive stages of diabetic retinopathy.Scientific reports · 2024Article
- Retinal Oxygen Metabolism in Patients With Type 2 Diabetes and Different Stages of Diabetic Retinopathy.Diabetes · 2022Article
- Diabetic macular ischaemia- a new therapeutic target?Progress in retinal and eye research · 2022Review
- Neuro-vascular coupling and heart rate variability in patients with type II diabetes at different stages of diabetic retinopathy.Frontiers in medicine · 2022Article
- Article
- Retina-specific targeting of pericytes reveals structural diversity and enables control of capillary blood flow.The Journal of comparative neurology · 2021Article
- Intravital Imaging of Circulating Red Blood Cells in the Retinal Vasculature of Growing Mice.Translational vision science & technology · 2021Article
- Predictive modelling of thrombus formation in diabetic retinal microaneurysms.Royal Society open science · 2020Article
- The pericyte connectome: spatial precision of neurovascular coupling is driven by selective connectivity maps of pericytes and endothelial cells and is disrupted in diabetes.Cell discovery · 2020Article
- Improved Macular Capillary Flow on Optical Coherence Tomography Angiography After Panretinal Photocoagulation for Proliferative Diabetic Retinopathy.American journal of ophthalmology · 2019Article
- Retinal Blood Velocity and Flow in Early Diabetes and Diabetic Retinopathy Using Adaptive Optics Scanning Laser Ophthalmoscopy.Journal of clinical medicine · 2019Article
- Hyperglycemia Enhances Constriction of Retinal Venules via Activation of the Reverse-Mode Sodium-Calcium Exchanger.Diabetes · 2019Article
- Does the scleral encircling band provide a protective effect against the progression of diabetic retinopathy?International journal of ophthalmology · 2019Article
- Constriction of Retinal Venules to Endothelin-1: Obligatory Roles of ETA Receptors, Extracellular Calcium Entry, and Rho Kinase.Investigative ophthalmology & visual science · 2018Article
- Optical coherence tomography angiography.Progress in retinal and eye research · 2018Review
- Decreased ocular blood flow after photocoagulation therapy in neonatal retinopathy of prematurity.Japanese journal of ophthalmology · 2017Article
- Evaluating ocular blood flow.Indian journal of ophthalmology · 2017Review
- Alterations in Retinal Vascular and Oxygen Metrics in Treated and Untreated Proliferative Diabetic Retinopathy: A Case Report.Case reports in ophthalmologyArticle
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Authors and funding
7 authors at 4 institutions in 1 country.
Funding
Abstract
purposeTo evaluate retinal blood flow measurements in normal eyes and eyes with varying levels of diabetic retinopathy (DR) using Doppler Fourier-domain optical coherence tomography (FD-OCT).
methodsTwenty-two eyes of 19 subjects, 10 with severe nonproliferative DR (NPDR) and 12 with proliferative DR (PDR), were compared with 44 eyes of 40 healthy control subjects. All eyes were scanned by RTvue FD-OCT. Color disk photographs and cube/volume scans of the optic nerve head were obtained. Doppler OCT scans and accessory imaging data were imported into Doppler OCT of Retinal Circulation grading software to calculate TRBF and vascular parameters (e.g., venous and arterial cross-sectional area). Measurements were compared between cases and controls using independent t-tests.
resultsMean TRBF was 44.98 ± 9.80 (range: 30.18-64.58) µL/minute for normal eyes, 35.80 ± 10.48 (range: 20.69-49.56) µL/minute for eyes with severe NPDR, and 34.79 ± 10.61 (range: 16.77-48.9) µL/minute for eyes with PDR. Mean TRBF was significantly lower in eyes with severe NPDR (P = 0.01) and PDR (P = 0.003) than in normal eyes.
conclusionTotal retinal blood flow was significantly lower in eyes with severe NPDR and PDR compared with normal eyes. Retinal blood flow determined by Doppler OCT may be a useful parameter for evaluating patients with DR.
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