Evidence map›Paper›PMID 28098524›Full record

ArticleEmerging infectious diseases2017

Swine Influenza Virus (H1N2) Characterization and Transmission in Ferrets, Chile.

Nicolás Bravo-Vasquez, Erik A Karlsson, Pedro Jimenez-Bluhm, Victoria Meliopoulos, Bryan Kaplan, Shauna Marvin, Valerie Cortez, Pamela Freiden, Melinda A Beck, Christopher Hamilton-West and 1 more

Open access · diamondAbstract read
In one paragraph

Article in Emerging infectious diseases, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Nicolás Bravo-Vasquez
Erik A Karlsson
Pedro Jimenez-Bluhm
Victoria Meliopoulos
Bryan Kaplan
Shauna Marvin
Valerie Cortez
Pamela Freiden
Melinda A Beck
Christopher Hamilton-West
Stacey Schultz-Cherry
University of Chile · CLUniversity of North Carolina at Chapel Hill · USSt. Jude Children's Research Hospital · US

Funding

NIAID NIH HHS HHSN272201400006C
6 · The paper itself

Abstract

Phylogenetic analysis of the influenza hemagglutinin gene (HA) has suggested that commercial pigs in Chile harbor unique human seasonal H1-like influenza viruses, but further information, including characterization of these viruses, was unavailable. We isolated influenza virus (H1N2) from a swine in a backyard production farm in Central Chile and demonstrated that the HA gene was identical to that in a previous report. Its HA and neuraminidase genes were most similar to human H1 and N2 viruses from the early 1990s and internal segments were similar to influenza A(H1N1)pdm09 virus. The virus replicated efficiently in vitro and in vivo and transmitted in ferrets by respiratory droplet. Antigenically, it was distinct from other swine viruses. Hemagglutination inhibition analysis suggested that antibody titers to the swine Chilean H1N2 virus were decreased in persons born after 1990. Further studies are needed to characterize the potential risk to humans, as well as the ecology of influenza in swine in South America.

Indexed as

Influenza A Virus, H1N2 SubtypeAnimal DiseasesAnimalsAntibodies, ViralCell LineChileFemaleFerretsGeography, MedicalHemagglutination Inhibition TestsHigh-Throughput Nucleotide SequencingHumansInfluenza, HumanOrthomyxoviridae InfectionsPublic Health SurveillanceRNA, ViralAntibodies, ViralRNA, Viralbackyard farmbackyard production systemChileH1N1 pandemic strainH1N2influenzainfluenza ASouth Americaswine influenza virustransmissionviruseszoonoses

Identifiers

PMID28098524
PMCPMC5324791
OpenAlexW2569862967

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.