Evidence map›Paper›PMID 28098320›Full record

ArticleLab on a chip2017

Versatile tissue lasers based on high-Q Fabry-Pérot microcavities.

Yu-Cheng Chen, Qiushu Chen, Tingting Zhang, Wenjie Wang, Xudong Fan

Open access · greenAbstract read
In one paragraph

Article in Lab on a chip, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 46 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Cellular Features Revealed by Transverse Laser Modes in Frequency Domain.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022
    Article
  8. Review
  9. Biophotonic probes for bio-detection and imaging.Light, science & applications · 2021
    Review
  10. Article
  11. Virus lasers for biological detection.Nature communications · 2019
    Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Yu-Cheng ChenDepartment of Biomedical Engineering, University of Michigan, 1101 Beal Ave., Ann Arbor, MI 48109, USA. xsfan@umich.edu.
Qiushu ChenDepartment of Biomedical Engineering, University of Michigan, 1101 Beal Ave., Ann Arbor, MI 48109, USA. xsfan@umich.edu.
Tingting ZhangKey Lab of Advanced Transducers and Intelligent Control System of Ministry of Education, Taiyuan University of Technology, 79 Yingze Street, Taiyuan 030024, PR China.
Wenjie WangKey Lab of Advanced Transducers and Intelligent Control System of Ministry of Education, Taiyuan University of Technology, 79 Yingze Street, Taiyuan 030024, PR China.
Xudong FanDepartment of Biomedical Engineering, University of Michigan, 1101 Beal Ave., Ann Arbor, MI 48109, USA. xsfan@umich.edu and Key Lab of Advanced Transducers and Intelligent Control System of Ministry of Education, Taiyuan University of Technology, 79 Yingze Street, Taiyuan 030024, PR China.ORCID 0000-0003-0149-1326
University of Michigan · USTaiyuan University of Technology · CN

Funding

Protein interaction study In-vitro and in live cells with optofluidic lasersR21EB016783 · NIBIB · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI FAN, XUDONG · 2014 to 2015
$403k
NIBIB NIH HHS R21 EB016783
6 · The paper itself

Abstract

Biolasers are an emerging technology for next generation biochemical detection and clinical applications. Progress has recently been made to achieve lasing from biomolecules and single living cells. Tissues, which consist of cells embedded in an extracellular matrix, mimic more closely the actual complex biological environment in a living body and therefore are of more practical significance. Here, we developed a highly versatile tissue laser platform, in which tissues stained with fluorophores are sandwiched in a high-Q Fabry-Pérot microcavity. Distinct lasing emissions from muscle and adipose tissues stained respectively with fluorescein isothiocyanate (FITC) and boron-dipyrromethene (BODIPY), and hybrid muscle/adipose tissue with dual staining were achieved with a threshold of only ∼10 μJ mm

Indexed as

LasersAdipose TissueAnimalsFluorescein-5-isothiocyanateFluorescent DyesMicroscopy, ConfocalModels, BiologicalMolecular ImagingMusclesSwineFluorescein-5-isothiocyanateFluorescent Dyes

Identifiers

PMID28098320
PMCPMC5289748
OpenAlexW2579669442

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.