ReviewDeutsches Arzteblatt international2016
The Differential Diagnosis of Dyspnea.
Review in Deutsches Arzteblatt international, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06524856 (The Increase of Lung Capacity Using the Lung Master), which is not on this map. Cited by 79 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Increase of Lung Capacity Using the Lung Master (Pulmonary Exerciser)
Who cites it
79 citing papers in PubMed, 2 syntheses or guidelines pooled it, 162 citations in OpenAlex.
- Diagnosis of heart failure with preserved ejection fraction: a systematic narrative review of the evidence.Heart failure reviews · 2024Pooled it
- Fixed-intensity exercise tests to measure exertional dyspnoea in chronic heart and lung populations: a systematic review.European respiratory review : an official journal of the European Respiratory Society · 2023Pooled it
- Effects of percutaneous coronary intervention on dyspnea in stable coronary artery disease.Clinical research in cardiology : official journal of the German Cardiac Society · 2023Trial
- Stroke in people living with HIV and 6-month outcomes in Northwestern Tanzania.Equity neuroscience · 2026Article
- Assessment of an Ultrasonography-Based Algorithm for Detecting the Causes of Acute Dyspnea in an Emergency Hospital.Medeniyet medical journal · 2026Article
- Article
- Point-of-care ultrasound improves the diagnosis of heart failure in patients with dyspnea in primary care.Frontiers in medicine · 2026Article
- Advances in diagnosis of lung fibrosis: focus on present and future approaches.Frontiers in medicine · 2026Review
- COPD-Asthma-Heart Failure Overlap: Optimizing Bronchodilators and ICS in a High-Risk Triad.Journal of asthma and allergy · 2026Review
- Dyspnea in Chronic Obstructive Pulmonary Disease: Expert Assessment of Management in Clinical Practice.Pulmonary therapy · 2025Article
- Optimizing Loop Diuretic Treatment for Mortality Reduction in Patients With Acute Dyspnea Using a Practical Offline Reinforcement Learning Pipeline for Health Care: Retrospective Single-Center Simulation Study.JMIR medical informatics · 2025Article
- The predictive role of dyspnea in left main and/or three-vessel coronary artery involvement in patients with myocardial infarction: an analytical cross-sectional study.BMC cardiovascular disorders · 2025Article
- Non-invasive neuromodulation for alleviating dyspnoea: protocol for a feasibility sham-controlled randomised trial.BMJ open · 2025Article
- Leveraging intrinsic non-sinusoidal patterns to infer search behavior to predict exposure to respiratory stressors.American journal of physiology. Lung cellular and molecular physiology · 2025Article
- Calprotectin in the risk stratification of patients with acute dyspnoea in the emergency department.Scientific reports · 2025Observational
- Vocal biomarkers correlate with FEV1 variations during methacholine challenge.Clinical and translational allergy · 2025Article
- Effects of Physical Exercise on Walking Distance and Functional Limitations in Patients with Chronic Dyspnea.Medicina (Kaunas, Lithuania) · 2025Article
- Hypercapnia Reduces Perceived Heat Pain in Healthy Subjects.European journal of pain (London, England) · 2025Article
- "I'm living in a 'no' world now…"- A qualitative study of the widespread impact of living with chronic breathlessness, and experiences of identification and assessment of this symptom in an older, frail community-based population.NPJ primary care respiratory medicine · 2025Article
- Costs of Adverse Events in Patients with Advanced or Metastatic Renal Cell Carcinoma with First-Line Treatment.PharmacoEconomics - open · 2025Article
19 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDyspnea is a common symptom affecting as many as 25% of patients seen in the ambulatory setting. It can arise from many different underlying conditions and is sometimes a manifestation of a life-threatening disease.
methodsThis review is based on pertinent articles retrieved by a selective search in PubMed, and on pertinent guidelines.
resultsThe term dyspnea refers to a wide variety of subjective perceptions, some of which can be influenced by the patient's emotional state. A distinction is drawn between dyspnea of acute onset and chronic dyspnea: the latter, by definition, has been present for more than four weeks. The history, physical examination, and observation of the patient's breathing pattern often lead to the correct diagnosis, yet, in 30-50% of cases, more diagnostic studies are needed, including biomarker measurements and other ancillary tests. The diagnosis can be more difficult to establish when more than one underlying disease is present simultaneously. The causes of dyspnea include cardiac and pulmonary disease (congestive heart failure, acute coronary syndrome; pneumonia, chronic obstructive pulmonary disease) and many other conditions (anemia, mental disorders).
conclusionThe many causes of dyspnea make it a diagnostic challenge. Its rapid evaluation and diagnosis are crucial for reducing mortality and the burden of disease.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.