Evidence map›Paper›PMID 28097739›Full record

ReviewDevelopmental dynamics : an official publication of the American Association of Anatomists2017

Cellular plasticity in cardiovascular development and disease.

Soumyashree Das, Kristy Red-Horse

Abstract readReview
In one paragraph

Review in Developmental dynamics : an official publication of the American Association of Anatomists, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Embryonic Chicken (Comparative medicine · 2019
    Review
  2. Foxc2 is required for proper cardiac neural crest cell migration, outflow tract septation, and ventricle expansion.Developmental dynamics : an official publication of the American Association of Anatomists · 2018
    Article
  3. Bmi1-Progenitor Cell Ablation Impairs the Angiogenic Response to Myocardial Infarction.Arteriosclerosis, thrombosis, and vascular biology · 2018
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Soumyashree DasDepartment of Biology, Stanford University, Stanford, California.
Kristy Red-HorseDepartment of Biology, Stanford University, Stanford, California.

Funding

Mechanotransduction and transcriptional regulation during artery developmentR01HL128503 · NHLBI · STANFORD UNIVERSITY · PI Mary Red-Horse · 2015 to 2026
$5.8M
NHLBI NIH HHS R01 HL128503
6 · The paper itself

Abstract

Knowledge on cellular differentiation pathways is critical to understanding organ development, homeostasis, and disease. Studying cell differentiation and cell fate restrictions in these contexts can be done through lineage tracing experiments, which entail permanent labeling of a cell and all its progeny. Recent lineage experiments within the cardiovascular system have uncovered unexpected findings on cellular origins during organogenesis and cell plasticity during disease. For example, there is increasing evidence that multiple progenitor sources exist for a single cell type, and that cells have remarkable expansive capacities under disease settings. Here, we summarize some recent findings in the cardiovascular system and highlight where there is evidence that the underlying concepts are a widespread phenomenon used by other organ systems. Developmental Dynamics 246:328-335, 2017. © 2016 Wiley Periodicals, Inc.

Indexed as

AnimalsCardiovascular DiseasesCardiovascular SystemCell DifferentiationCell LineageCell PlasticityHumansOrganogenesisStem Cellscardiovascular systemclonal analysisgenetic lineage tracingprogenitor cells

Identifiers

PMID28097739
PMCPMC5489309

What OpenQuestion holds

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LicenceTDM
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.