ArticleJournal of veterinary internal medicine2017
Thromboelastography in Dogs with Chronic Hepatopathies.
Article in Journal of veterinary internal medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 54 citations in OpenAlex.
- An Explorative Study of Haemostasis in Canine Steroid-Responsive Meningitis-Arteritis Using Viscoelastic Monitoring.Animals : an open access journal from MDPI · 2025Article
- Development of Reference Intervals for the TEG 6s, a Point-of-Care Viscoelastic Assay, in Dogs.Veterinary clinical pathology · 2025Article
- Hypercoagulability identified in dogs with chronic enteropathy using a point-of-care viscoelastic assay.The Journal of small animal practice · 2025Article
- Thromboelastography in dogs with idiopathic epilepsy treated with phenobarbital monotherapy.Veterinary clinical pathology · 2024Article
- Evaluation of the effect of etamsylate on thromboelastographic traces of canine blood with and without the addition of heparin.The veterinary quarterly · 2023Article
- Fibrinolysis in Dogs with Intracavitary Effusion: A Review.Animals : an open access journal from MDPI · 2022Review
- Point-of-care viscoelastic coagulation assessment in healthy dogs during the perianesthetic period.BMC veterinary research · 2022Article
- Comparison of assessment of coagulation in healthy dogs by the TEG 6s and TEG 5000 viscoelastic analyzers.Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc · 2022Article
- 2022 Update of the Consensus on the Rational Use of Antithrombotics and Thrombolytics in Veterinary Critical Care (CURATIVE) Domain 1- Defining populations at risk.Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001) · 2022Article
- Hemostatic Analysis of SimulatedAnimals : an open access journal from MDPI · 2022Article
- Pre-operative Hemostatic Status in Dogs Undergoing Splenectomy for Splenic Masses.Frontiers in veterinary science · 2022Article
- Impact of general anesthesia on rotational thromboelastometry (ROTEM) parameters and standard plasmatic coagulation tests in healthy Beagle dogs.Veterinary and animal science · 2021Article
- Evaluation of coagulation parameters in dogs with gallbladder mucoceles.Journal of veterinary internal medicine · 2021Article
- Hypercoagulability in dogs with chronic enteropathy and association with serum albumin concentration.Journal of veterinary internal medicine · 2021Article
- Coagulation status, fibrinolysis, and platelet dynamics in dogs with chronic inflammatory enteropathy.Journal of veterinary internal medicine · 2021Article
- Thromboelastography in cats with cholestatic liver disease.Journal of feline medicine and surgery · 2021Article
- Hemorrhage and complications associated with percutaneous ultrasound guided liver biopsy in dogs.Journal of veterinary internal medicine · 2020Article
- ACVIM consensus statement on the diagnosis and treatment of chronic hepatitis in dogs.Journal of veterinary internal medicine · 2019Article
- Hepatic Fibrosis in Dogs.Journal of veterinary internal medicine · 2018Review
- Hemostatic profiles in dogs with sudden acquired retinal degeneration syndrome.Journal of veterinary internal medicineArticle
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe coagulation status of dogs with liver disease is difficult to predict using conventional coagulation testing. HYPOTHESIS/
objectivesTo evaluate thromboelastography (TEG) results and associations with conventional coagulation results and indicators of disease severity and prognosis in dogs with chronic hepatopathies (CH). ANIMALS: Twenty-one client-owned dogs.
methodsDogs with CH were prospectively (10 dogs) and retrospectively (11 dogs) enrolled from 2008 to 2014. Kaolin-activated TEG was performed and compared with reference intervals by t-tests or Mann-Whitney tests. Correlation coefficients for TEG results and conventional coagulation and clinicopathologic results were determined. Significance was set at P < .05.
resultsDogs with CH had significant increases in R (5.30 min vs 4.33 min), K (3.77 min vs 2.11 min), and LY30 (4.77% vs 0.68%) and decreased angles (55.3° vs 62.4°). G value defined 9 of 21, 7 of 21, and 5 of 21 dogs as normocoagulable, hypercoagulable, and hypocoagulable, respectively. G and MA were correlated with fibrinogen (r = 0.68, 0.83), prothrombin time (PT; r = -0.51, -0.53), and activated partial thromboplastin time (aPTT; r = -0.50, -0.50). K was correlated with PT (r = 0.75) and protein C activity (r = -0.92). Angle was correlated with aPTT (r = -0.63). Clinical score was correlated with PT (r = 0.60), MA (r = -0.53), and R (r = -0.47). Dogs with hyperfibrinolysis (LY30 > 3.04%; 5 of 21) had significantly higher serum transaminase activities. Dogs with portal hypertension had significantly lower G, MA, and angle and prolonged, K, R, and PT. CONCLUSIONS AND CLINICAL RELEVANCE: Dogs with CH have variable TEG results. Negative prognostic indicators in CH correlate with hypocoagulable parameters on TEG. Hyperfibrinolysis in dogs with CH is associated with high disease activity.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.