Evidence map›Paper›PMID 28097603›Full record

ArticleInternational journal of computer assisted radiology and surgery2017

Comprehensive preclinical evaluation of a multi-physics model of liver tumor radiofrequency ablation.

Chloé Audigier, Tommaso Mansi, Hervé Delingette, Saikiran Rapaka, Tiziano Passerini, Viorel Mihalef, Marie-Pierre Jolly, Raoul Pop, Michele Diana, Luc Soler and 3 more

Abstract readValidation Study
PubMed Publisher
In one paragraph

Article in International journal of computer assisted radiology and surgery, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Trial
  2. Review
  3. Review
  4. Article
  5. Computer-assisted planning for a concentric tube robotic system in neurosurgery.International journal of computer assisted radiology and surgery · 2019
    Article
  6. Ultrasound thermal monitoring with an external ultrasound source for customized bipolar RF ablation shapes.International journal of computer assisted radiology and surgery · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Chloé AudigierUniversité Côte d'Azur and Inria Sophia-Antipolis Méditerranée Asclepios team, Inria Sophia Antipolis, France. chloe.audigier@inria.fr.ORCID http://orcid.org/0000-0002-8443-1873
Tommaso MansiMedical Imaging Technologies, Siemens Healthcare, Princeton, NJ, USA.
Hervé DelingetteUniversité Côte d'Azur and Inria Sophia-Antipolis Méditerranée Asclepios team, Inria Sophia Antipolis, France.
Saikiran RapakaMedical Imaging Technologies, Siemens Healthcare, Princeton, NJ, USA.
Tiziano PasseriniMedical Imaging Technologies, Siemens Healthcare, Princeton, NJ, USA.
Viorel MihalefMedical Imaging Technologies, Siemens Healthcare, Princeton, NJ, USA.
Marie-Pierre JollyMedical Imaging Technologies, Siemens Healthcare, Princeton, NJ, USA.
Raoul PopIHU - Institut de Chirugie Guidée Par L'Image, Strasbourg, France.
Michele DianaIHU - Institut de Chirugie Guidée Par L'Image, Strasbourg, France.
Luc SolerIHU - Institut de Chirugie Guidée Par L'Image, Strasbourg, France.
Ali KamenMedical Imaging Technologies, Siemens Healthcare, Princeton, NJ, USA.
Dorin ComaniciuMedical Imaging Technologies, Siemens Healthcare, Princeton, NJ, USA.
Nicholas AyacheUniversité Côte d'Azur and Inria Sophia-Antipolis Méditerranée Asclepios team, Inria Sophia Antipolis, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWe aim at developing a framework for the validation of a subject-specific multi-physics model of liver tumor radiofrequency ablation (RFA).

methodsThe RFA computation becomes subject specific after several levels of personalization: geometrical and biophysical (hemodynamics, heat transfer and an extended cellular necrosis model). We present a comprehensive experimental setup combining multimodal, pre- and postoperative anatomical and functional images, as well as the interventional monitoring of intra-operative signals: the temperature and delivered power.

resultsTo exploit this dataset, an efficient processing pipeline is introduced, which copes with image noise, variable resolution and anisotropy. The validation study includes twelve ablations from five healthy pig livers: a mean point-to-mesh error between predicted and actual ablation extent of 5.3 ± 3.6 mm is achieved.

conclusionThis enables an end-to-end preclinical validation framework that considers the available dataset.

Indexed as

AnimalsCatheter AblationHemodynamicsLiverLiver NeoplasmsModels, AnimalNecrosisSwineComputational modelingPreclinical evaluationRadiofrequency ablation

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.