Trial reportAnnals of behavioral medicine : a publication of the Society of Behavioral Medicine2017
Distress is Interdependent in Patients and Caregivers with Newly Diagnosed Incurable Cancers.
Trial report in Annals of behavioral medicine : a publication of the Society of Behavioral Medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02349412 (Randomized Study of Early Palliative Care Integrated With Standard Oncology Care Versus Standard Oncology Care Alone in Patients With Incurable Lung or Non-Colorectal Gastrointestinal Malignancies), which is not on this map. Cited by 82 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Randomized Study of Early Palliative Care Integrated With Standard Oncology Care Versus Standard Oncology Care Alone in Patients With Incurable Lung or Non-Colorectal Gastrointestinal Malignancies
Who cites it
82 citing papers in PubMed, 1 synthesis or guideline pooled it, 127 citations in OpenAlex.
- Nonpharmacologic interventions for managing distress, anxiety, and depression for patients with cancer and their family caregivers: A systematic review and meta-analysis.CA: a cancer journal for cliniciansPooled it
- Improved coping and self-efficacy drive improvements in mood among caregivers of patients with primary malignant brain tumors: Results from a randomized controlled trial.Neuro-oncology · 2026Trial
- The family caregiver-targeted web-based intervention "narstaende.se" facilitated everyday life for couples facing life-threatening illness: A qualitative study.Palliative medicine · 2025Trial
- The shared uncertainty experience of older adults with advanced cancer and their caregivers.Psycho-oncology · 2022Trial
- Emotional distress in neuro-ICU survivor-caregiver dyads: The recovering together randomized clinical trial.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2022Trial
- A randomized wait-list controlled trial of a social support intervention for caregivers of patients with primary malignant brain tumor.BMC health services research · 2021Trial
- Trial
- Dyadic yoga program for patients undergoing thoracic radiotherapy and their family caregivers: Results of a pilot randomized controlled trial.Psycho-oncology · 2019Trial
- Effect of home-based specialised palliative care and dyadic psychological intervention on caregiver anxiety and depression: a randomised controlled trial.British journal of cancer · 2018Trial
- Needs of Rural Caregivers of Patients With Cancer: A Scoping Review of Evidence From North America, Europe, and Australia.Psycho-oncology · 2026Article
- Impact of caregiver cancer stigma on treatment adherence in newly diagnosed cancer patients: a prospective study.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026Article
- Exploring the understanding and management of anxiety from cancer in Latino/a older adults and their caregivers.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
- Considering the caregiver in early-phase clinical trials: a review of trial protocols and consent forms.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Review
- Loneliness within couples coping with cancer: prevalence, associations with physical and mental health, and potential benefits of dyadic exercise.Frontiers in aging · 2026Article
- Exploring the anxiety, depression and perceived burden in advanced cancer: A longitudinal view on patients and caregivers.Palliative & supportive care · 2025Article
- Psychological distress in newly diagnosed patients with gastrointestinal cancer: A scoping review.Asia-Pacific journal of oncology nursing · 2025Review
- Spiritual Well-Being and Care Burden among Families of Patients with Terminal Cancer: Is Emotional Distress a Crucial Thing?Journal of hospice and palliative care · 2025Article
- Mediating effect of dyadic coping between family function and meaning in life in patients with advanced lung cancer.BMC psychology · 2025Article
- Caregiver experiences managing information prior to hematopoietic stem cell transplantation and after transition to home: a qualitative study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Article
- Barriers to accessing formal cancer care from the perspective of informal caregivers: a qualitative study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Article
22 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundIndividuals with advanced, incurable cancer often experience high physical and psychological symptom burden. Family and friend caregivers are at risk for emotional distress. PURPOSE: The aim of the study is to investigate the interrelationship of distress in patient-caregiver dyads at the time of newly diagnosed incurable cancer.
methodsFrom May 2011 to July 2015, within 8 weeks of diagnosis of advanced lung or noncolorectal gastrointestinal cancer, 350 patients and 275 family caregivers were enrolled in a randomized controlled trial of early palliative care. Actor-partner interdependence modeling was used to examine relationships between dyad's self-reported anxiety and depressive symptoms on the Hospital Anxiety and Depression Scale at baseline.
resultsComparing patients with caregivers, patients reported more depressive symptoms (M
conclusionsIn the context of newly diagnosed incurable cancer, caregivers experience more pronounced anxiety, while patients report greater depressive symptoms. Findings indicate that anxiety and depressive symptoms are interrelated among dyads facing newly diagnosed incurable disease. Results emphasize the importance of addressing distress in both patients and caregivers. Future research should discern when dyadic versus individual psychosocial interventions would be optimal. TRIAL REGISTRATION NUMBER: The trial was registered with the ClinicalTrials.gov database (NCT02349412) https://clinicaltrials.gov/ct2/show/NCT02349412 .
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.