Evidence map›Paper›PMID 28097378›Full record

ArticleDer Pathologe2017

[Molecular pathogenesis of Duchenne muscular dystrophy-related fibrosis].

K Ohlendieck, D Swandulla

Open access · hybridAbstract read
PubMed Publisher
In one paragraph

Article in Der Pathologe, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Serum protein biomarker signature of Duchenne muscular dystrophy.European journal of translational myology · 2025
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  5. Review
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  8. Review
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  10. Article
  11. Current Pharmacological Strategies for Duchenne Muscular Dystrophy.Frontiers in cell and developmental biology · 2021
    Review
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  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

K OhlendieckMuscle Biology Laboratory, Department of Biology, Maynooth University, National University of Ireland, Maynooth, Co. Kildare, Irland. kay.ohlendieck@nuim.ie.
D SwandullaInstitut für Physiologie 2, Rheinische Friedrich-Wilhelms-Universität Bonn, Bonn, Deutschland.
National University of Ireland, Maynooth · IEUniversity of Bonn · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Progressive myofibrosis plays a key role in Duchenne muscular dystrophy. The dystrophic loss of contractile cells triggers a relatively nonspecific restructuring of the surrounding mesenchyme. The increase in connective and fatty tissue leads to muscular weakness and is therefore of critical importance for the cellular pathogenesis of muscular dystrophy. The systematic biochemical analysis of fibrosis using comparative proteomics has identified a number of extracellular matrix proteins that are indirectly involved in muscular dystrophy. An increased concentration was established for collagen I, collagen IV, collagen VI, periostin, dermatopontin, fibronectin, biglycan, asporin, decorin, prolargin, mimecan and lumican. Based on these findings, the identified matrix proteins can now be characterized biochemically and their exact pathophysiological role in Duchenne muscular dystrophy determined.

Indexed as

Cell Adhesion MoleculesDystrophinExtracellular Matrix ProteinsFibrosisHumansMuscle, SkeletalMuscular Dystrophy, DuchenneProteomicsCell Adhesion MoleculesDMD protein, humanDystrophinExtracellular Matrix ProteinsPOSTN protein, humanCollagenDystrophinMuscle proteomeMyofibrosisPeriostin

Identifiers

PMID28097378
OpenAlexW2580534958

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.