Evidence map›Paper›PMID 28097219›Full record

ArticleScience advances2017

Key role of the dopamine D

Jordi Bonaventura, César Quiroz, Ning-Sheng Cai, Marcelo Rubinstein, Gianluigi Tanda, Sergi Ferré

Open access · goldAbstract read
In one paragraph

Article in Science advances, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 2 pooled it
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 2 syntheses or guidelines pooled it, 57 citations in OpenAlex.

  1. Putative Animal Models of Restless Legs Syndrome: A Systematic Review and Evaluation of Their Face and Construct Validity.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2023
    Pooled it
  2. Pooled it
  3. An emerging role for synaptic ZnPharmacology & therapeutics · 2026
    Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Structural Studies of the Dopamine DACS medicinal chemistry letters · 2025
    Article
  9. Article
  10. Humanized dopamine DJournal of neuroscience research · 2024
    Review
  11. Article
  12. Review
  13. Article
  14. Article
  15. The ADORA1 mutation linked to early-onset Parkinson's disease alters adenosine ABiomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2022
    Article
  16. Review
  17. Article
  18. Attention-deficit/hyperactive disorder updates.Frontiers in molecular neuroscience · 2022
    Review
  19. Review
  20. Synaptic ZnTranslational psychiatry · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Jordi BonaventuraIntegrative Neurobiology Section, National Institute on Drug Abuse, Intramural research Program, National Institutes of Health, Baltimore, MD 21224, USA.ORCID 0000-0002-4745-0151
César QuirozIntegrative Neurobiology Section, National Institute on Drug Abuse, Intramural research Program, National Institutes of Health, Baltimore, MD 21224, USA.
Ning-Sheng CaiIntegrative Neurobiology Section, National Institute on Drug Abuse, Intramural research Program, National Institutes of Health, Baltimore, MD 21224, USA.
Marcelo RubinsteinInstitute of Investigation in Genetic Engineering and Molecular Biology, Buenos Aires 1428, Argentina.
Gianluigi TandaMedications Development Program, National Institute on Drug Abuse, Intramural research Program, National Institutes of Health, Baltimore, MD 21224, USA.ORCID 0000-0001-9526-9878
Sergi FerréIntegrative Neurobiology Section, National Institute on Drug Abuse, Intramural research Program, National Institutes of Health, Baltimore, MD 21224, USA.
National Institutes of Health · USInstitute of Molecular Genetics · RUNational Institute on Drug Abuse · US

Funding

Neurotransmitter Receptor Heteromers in the Striatal Spine ModuleZIADA000493 · NIDA · NATIONAL INSTITUTE ON DRUG ABUSE · PI FERRE, SERGI · 2009 to 2025
$35.6M
Investigation On The Behavior And Related Neuro-Electrochemistry Of Potential Medications For The Treatment Of Substance Use Disorders.ZIADA000611 · NIDA · NATIONAL INSTITUTE ON DRUG ABUSE · PI TANDA, GIANLUIGI · 2016 to 2025
$16.0M
Endocannabinoid roles in neurochemical and reinforcing effects of abused drugsZIADA000569 · NIDA · NATIONAL INSTITUTE ON DRUG ABUSE · PI TANDA, GIANLUIGI · 2010 to 2020
$6.7M
6 · The paper itself

Abstract

Polymorphic variants of the dopamine D

Indexed as

Synaptic TransmissionAnimalsAttention Deficit Disorder with HyperactivityCorpus StriatumGene Knock-In TechniquesGlutamic AcidHumansMiceMice, TransgenicProtein DomainsReceptors, Dopamine D4Glutamic AcidReceptors, Dopamine D4attention deficit hyperactivity disorderbasal gangliadopamineDopamine D4 receptorglutamatemethamphetaminepolymorphic variantsubstance use disorders

Identifiers

PMID28097219
PMCPMC5226642
OpenAlexW2576832595

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.