ArticleMolecular biology research communications2016
In silico comparison of Iranian HIV -1 envelop glycoprotein with five nearby countries.
Article in Molecular biology research communications, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
1 citing paper in PubMed, 1 citations in OpenAlex.
- Analysis and comparison of physiochemical properties, mutations and glycosylation patterns between RNA polymerase and membrane protein of SARS-CoV and SARS-CoV-2.Molecular biology research communications · 2021Article
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
HIV-1 envelope (env) glycoprotein mediates an important role in entry of the virus into the susceptible target cells. As env glycoprotein of HIV-1 is highly variable in the different geographical regions, in the present study, different properties of this protein in Iran are compared with five nearby countries. The sequences of HIV-1 env glycoproteins of Iran, Afghanistan, Russia, Turkey, Pakistan and Saudi Arabia databases were collected from databases. Amino acid composition and physical and chemical properties of the proteins from these countries were studied using Protparam and COPid tools. Receiver-operating characteristic (ROC) curve analysis and Support Vector Machine (SVM) were used to evaluate association between the properties of HIV-1 env glycoprotein of Iran with five nearby countries. The results verify that amino acid composition and four physical and chemical properties (molecular weight, isoelectric point, Aliphatic Index, and grand average of hydropathicity) of HIV-1 env protein in Iran and Russia were not significantly different. In conclusion, the results indicate that in silico techniques provide valuable information for comparing HIV-1 envelop glycoprotein in different geographical locations.
Indexed as
Identifiers
28097165PMC5219901W2416472415What OpenQuestion holds
Registered trials
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