Evidence map›Paper›PMID 28096978›Full record

ArticleAntimicrobial resistance and infection control2017

Carriage of antibiotic-resistant

Marcelyn T Magwenzi, Muchaneta Gudza-Mugabe, Hilda A Mujuru, Mutsa Dangarembizi-Bwakura, Valerie Robertson, Alexander M Aiken

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antimicrobial resistance and infection control, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 3 pooled it
0.7field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 3 syntheses or guidelines pooled it, 27 citations in OpenAlex.

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  13. Fever in the Returning Traveler.Infectious disease clinics of North America · 2018
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Marcelyn T MagwenziCollege of Health Sciences, Department of Medical Microbiology, University of Zimbabwe, PO Box A178, Harare, Zimbabwe.ORCID 0000-0002-1371-8615
Muchaneta Gudza-MugabeNational Microbiology Reference Laboratory, Harare Central Hospital, Harare, Zimbabwe.
Hilda A MujuruCollege of Health Sciences, Department of Paediatrics and Child Health, University of Zimbabwe, Harare, Zimbabwe ; Harare Central Hospital, Harare, Zimbabwe.
Mutsa Dangarembizi-BwakuraCollege of Health Sciences, Department of Paediatrics and Child Health, University of Zimbabwe, Harare, Zimbabwe ; Parirenyatwa Group of Hospitals, Harare, Zimbabwe.
Valerie RobertsonCollege of Health Sciences, Department of Medical Microbiology, University of Zimbabwe, PO Box A178, Harare, Zimbabwe ; Biomedical Research and Training Institute, Harare, Zimbabwe.
Alexander M AikenBiomedical Research and Training Institute, Harare, Zimbabwe ; London School of Hygiene and Tropical Medicine, London, UK.
University of Zimbabwe · ZWBiomedical Research and Training Institute · ZWHarare Central Hospital · ZW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundExtended-spectrum β-lactamase-producing and gentamicin resistant

methodsWe conducted a cohort study in paediatric inpatients at two tertiary-referral hospitals between May and July 2015. Rectal swabs and faecal samples were collected within 24 h of admission and further follow-up samples were collected on alternate days during hospitalization. Disc-based, selective and enrichment methods were used to detect carriage of these two forms of resistance. Standard methods were used to confirm resistance status and determine the susceptibility of resistant isolates to other commonly-used antibiotics.

resultsOne hundred and sixty four paediatric inpatient admissions (median age = 1.0 year, IQR = 0.2-2.2years) were enrolled, and an average of 1.9 faecal samples per patient were collected. On admission, 68/164 (41%) patients had both ESBL and gentamicin-resistant

conclusionsMore than half of children had enteric carriage of a clinically-relevant form of antibiotic resistance on admission to public-sector hospitals in urban Zimbabwe. Additionally, a fifth of children acquired a further form of resistance during hospitalisation. Urgent action is needed to tackle the spread of antibiotic resistant enteric bacteria in African hospitals.

Indexed as

Antibiotic resistanceChildrenColonizationEnterobacteriaceaeESBL

Identifiers

PMID28096978
PMCPMC5225579
OpenAlexW2573671991

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.