ReviewOncoTargets and therapy2017
Pediatric papillary thyroid cancer: current management challenges.
Review in OncoTargets and therapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 54 citations in OpenAlex.
- 2022 European Thyroid Association Guidelines for the management of pediatric thyroid nodules and differentiated thyroid carcinoma.European thyroid journal · 2022Guideline
- Thyroid Cancer: Epidemiology, Classification, Risk Factors, Diagnostic and Prognostic Markers, and Current Treatment Strategies.International journal of molecular sciences · 2025Review
- PCDH8 is a novel prognostic biomarker in thyroid cancer and promotes cell proliferation and viability.Functional & integrative genomics · 2024Article
- Thyroid nodules in children and adolescents: Investigation and management.Journal of paediatrics and child health · 2022Review
- Glutathione peroxidase 4 inhibition induces ferroptosis and mTOR pathway suppression in thyroid cancer.Scientific reports · 2022Article
- Article
- Identification of ferroptosis genes in immune infiltration and prognosis in thyroid papillary carcinoma using network analysis.BMC genomics · 2021Article
- Papillary thyroid carcinoma in a 7-year-old boy presenting with a goitre without microcalcifications and enlarged cervical lymph nodes.BMJ case reports · 2021Article
- Papillary Thyroid Carcinoma in Children: Clinicopathological Profile and Outcomes of Management.World journal of surgery · 2021Article
- Diffuse Sclerosing Variant of Papillary Thyroid Carcinoma in a Child: A Case Report.Taehan Yongsang Uihakhoe chi · 2020Article
- Initial treatment of pediatric differentiated thyroid cancer: a review of the current risk-adaptive approach.Pediatric radiology · 2019Review
- Vascular anomaly imaging mimics and differential diagnoses.Pediatric radiology · 2019Review
- RNA-sequencing investigation identifies an effective risk score generated by three novel lncRNAs for the survival of papillary thyroid cancer patients.Oncotarget · 2017Article
- Is There a Role for External Radiation Therapy in Pediatric Differentiated Thyroid Cancer?Journal of Indian Association of Pediatric SurgeonsArticle
- An 8 miRNA-Based Risk Score System for Predicting the Prognosis of Patients With Papillary Thyroid Cancer.Technology in cancer research & treatmentArticle
- Papillary thyroid cancer in prepubertal patients: A report of two cases and a brief review of the literature.Medicine internationalArticle
- Papillary thyroid carcinoma in a 5-year old child, mimicking lymphoma in presentation.Avicenna journal of medicineArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although with a standardized incidence of 0.54 cases per 100,000 persons, differentiated thyroid cancer (DTC) is a rare disease in children and adolescents, it nonetheless concerns ~1.4% of all pediatric malignancies. Furthermore, its incidence is rising. Due to the rarity and long survival of pediatric DTC patients, in most areas of treatment little evidence exists. Treatment of pediatric DTC is therefore littered with controversies, many questions therefore remain open regarding the optimal management of pediatric papillary thyroid cancer (PTC), and many challenges remain unsolved. In the present review, we aim to provide an overview of these challenging areas of patient and disease management in pediatric PTC patients. Data on diagnosis, surgery, radionuclide, and endocrine therapy are discussed, and the controversies therein are highlighted.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.