Evidence map›Paper›PMID 28096519›Full record

ArticleRNA (New York, N.Y.)2017

The nuclear poly(A) binding protein of mammals, but not of fission yeast, participates in mRNA polyadenylation.

Uwe Kühn, Juliane Buschmann, Elmar Wahle

Open access · bronzeAbstract read
In one paragraph

Article in RNA (New York, N.Y.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 40 citations in OpenAlex.

  1. Analysis ofMicroorganisms · 2026
    Article
  2. Poly(A) tail regulation in stem cells and early development.Cell regeneration (London, England) · 2025
    Review
  3. Article
  4. Review
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  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Sex Lethal Gene Manipulates Gonadal Development of Medaka,International journal of molecular sciences · 2022
    Article
  16. Molecular Insights into mRNA Polyadenylation and Deadenylation.International journal of molecular sciences · 2022
    Review
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Uwe KühnInstitute of Biochemistry and Biotechnology, Martin Luther University Halle-Wittenberg, 06099 Halle, Germany.
Juliane BuschmannInstitute of Biochemistry and Biotechnology, Martin Luther University Halle-Wittenberg, 06099 Halle, Germany.
Elmar WahleInstitute of Biochemistry and Biotechnology, Martin Luther University Halle-Wittenberg, 06099 Halle, Germany.ORCID 0000-0003-2504-0677
Martin Luther University Halle-Wittenberg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The nuclear poly(A) binding protein (PABPN1) has been suggested, on the basis of biochemical evidence, to play a role in mRNA polyadenylation by strongly increasing the processivity of poly(A) polymerase. While experiments in metazoans have tended to support such a role, the results were not unequivocal, and genetic data show that the

Indexed as

Cloning, MolecularEscherichia coliGene ExpressionGene Expression RegulationHEK293 CellsHumansIsoenzymesPoly APoly(A)-Binding Protein IPoly(A)-Binding ProteinsPolyadenylationPolynucleotide AdenylyltransferaseRecombinant ProteinsRNA, MessengerRNA PrecursorsSchizosaccharomycesIsoenzymesPab2 protein, S pombePABPN1 protein, humanPoly APoly(A)-Binding Protein IPoly(A)-Binding ProteinsPolynucleotide AdenylyltransferaseRecombinant ProteinsRNA, MessengerRNA PrecursorsSchizosaccharomyces pombe ProteinsmRNA polyadenylationpoly(A) binding proteinpoly(A) polymerasepre-mRNA 3′processing

Identifiers

PMID28096519
PMCPMC5340911
OpenAlexW2573372256

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.