Evidence map›Paper›PMID 28096308›Full record

ArticleJournal of the American Society of Nephrology : JASN2017

(Re)Building a Kidney.

Leif Oxburgh, Thomas J Carroll, Ondine Cleaver, Daniel R Gossett, Deborah K Hoshizaki, Jeffrey A Hubbell, Benjamin D Humphreys, Sanjay Jain, Jan Jensen, David L Kaplan and 11 more

Open access · greenAbstract read
In one paragraph

Article in Journal of the American Society of Nephrology : JASN, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 76 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Frontiers in bioengineering and biotechnology · 2025
    Article
  8. Article
  9. Article
  10. Spatial transcriptomics in health and disease.Nature reviews. Nephrology · 2024
    Review
  11. Article
  12. 3D Hydrogel Encapsulation Regulates Nephrogenesis in Kidney Organoids.Advanced materials (Deerfield Beach, Fla.) · 2024
    Article
  13. Review
  14. In Vivo Assessment of Laboratory-Grown Kidney Tissue Grafts.Bioengineering (Basel, Switzerland) · 2023
    Article
  15. Article
  16. Article
  17. Review
  18. Review
  19. How to Get Started with Single Cell RNA Sequencing Data Analysis.Journal of the American Society of Nephrology : JASN · 2021
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 16 institutions in 2 countries.

Leif OxburghCenter for Molecular Medicine, Maine Medical Center Research Institute, Scarborough, Maine; oxburl@mmc.org idrummond@mgh.harvard.edu.
Thomas J CarrollDepartment of Molecular Biology and.
Ondine CleaverDepartment of Molecular Biology and.
Daniel R GossettDivision of Kidney, Urologic, & Hematologic Diseases, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland.
Deborah K HoshizakiDivision of Kidney, Urologic, & Hematologic Diseases, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland.
Jeffrey A HubbellInstitute for Molecular Engineering, University of Chicago, Chicago, Illinois.
Benjamin D HumphreysDivision of Nephrology, Washington University School of Medicine, St. Louis, Missouri.
Sanjay JainDivision of Nephrology, Washington University School of Medicine, St. Louis, Missouri.
Jan JensenDepartment of Stem Cell Biology and Regenerative Medicine and.
David L KaplanDepartment of Biomedical Engineering, Tufts University, Medford, Massachusetts.
Carl KesselmanEpstein Department of Industrial and Systems Engineering and Information Sciences Institute, Viterbi School of Engineering and.
Christian J KetchumDivision of Kidney, Urologic, & Hematologic Diseases, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland.
Melissa H LittleCell Biology Theme, Murdoch Childrens Research Institute, Parkville, Melbourne, Australia.
Andrew P McMahonDepartment of Stem Cell Biology and Regenerative Medicine, Keck School of Medicine of the University of Southern California, Los Angeles, California.
Stuart J ShanklandDivision of Nephrology and.
Jason R SpenceDepartment of Internal Medicine, Division of Gastroenterology and.
M Todd ValeriusDepartment of Medicine, Brigham and Women's Hospital, Boston, Massachusetts.
Jason A WertheimDepartment of Surgery, Jesse Brown VA Medical Center, and.
Oliver WesselyDepartment of Cellular and Molecular Medicine, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio.
Ying ZhengDepartment of Bioengineering, Institute for Stem Cell and Regenerative Medicine, University of Washington, Seattle.
Iain A DrummondNephrology Division, Massachusetts General Hospital, Charlestown, Massachusetts.
National Institute of Diabetes and Digestive and Kidney Diseases · USThe University of Texas Southwestern Medical Center · USUniversity of Southern California · USWashington University in St. Louis · USBrigham and Women's Hospital · USCleveland Clinic Lerner College of Medicine · USJesse Brown VA Medical Center · USMaine Medical Center Research Institute · USMassachusetts General Hospital · USNational Institutes of Health · USOrganogenesis (United States) · USPediatric Nephrology of Alabama · USTufts University · USUniversity of Chicago · USUniversity of Melbourne · AUUniversity of Washington · US

Funding

The USC (Re)Building the Kidney Coordinating CenterU01DK107350 · NIDDK · UNIVERSITY OF SOUTHERN CALIFORNIA · PI KESSELMAN, CARL, VALERIUS, MICHAEL TODD · 2015 to 2019
$9.0M
Cell Interactions in Development of the Mammalian KidneyR37DK054364 · NIDDK · UNIVERSITY OF SOUTHERN CALIFORNIA · PI MCMAHON, ANDREW P. · 2008 to 2017
$7.0M
Engineering erythropoietin-producing cellsR24DK106743 · NIDDK · ROGOSIN INSTITUTE · PI CARROLL, THOMAS JOSEPH, CLEAVER, ONDINE B · 2015 to 2019
$7.0M
GUDMAP2 - Production of Mouse Strains for Gene Anatomy of the Lower Urinary TractU01DK094526 · NIDDK · UNIVERSITY OF SOUTHERN CALIFORNIA · PI MCMAHON, ANDREW P. · 2011 to 2015
$2.5M
Engineering Growth Factor-ECM Interactions to Heal Chronic Wounds in Type 1 DiabetesDP3DK108215 · NIDDK · UNIVERSITY OF CHICAGO · PI HUBBELL, JEFFREY A. · 2015 to 2015
$1.5M
Mechanisms of tubule interconnectionUH3DK107372 · NIDDK · MOUNT DESERT ISLAND BIOLOGICAL LAB · PI DRUMMOND, IAIN A. · 2017 to 2019
$1.3M
Differentiation of Human Pluripotent Stem Cells into Kidney Cell LineagesUH3DK107357 · NIDDK · CLEVELAND CLINIC LERNER COM-CWRU · PI JENSEN, JAN, WESSELY, OLIVER · 2017 to 2019
$1.2M
Rebuilding the glomerular filtration barrier by regenerating adult podocytesUH2DK107343 · NIDDK · UNIVERSITY OF WASHINGTON · PI SHANKLAND, STUART JAMES, ZHENG, YING · 2015 to 2016
$855k
Differentiation of Human Pluripotent Stem Cells into Kidney Cell LineagesUH2DK107357 · NIDDK · CLEVELAND CLINIC LERNER COM-CWRU · PI JENSEN, JAN, WESSELY, OLIVER · 2015 to 2016
$808k
Generating kidney organoids and mature renal cell types via directed iPSC differentiationUH2DK107344 · NIDDK · MURDOCH CHILDREN'S RESEARCH INSTITUTE · PI LITTLE, MELISSA HELEN · 2015 to 2016
$691k
Adult Progenitors in Kidney TubulointerstitiumUH2DK107374 · NIDDK · WASHINGTON UNIVERSITY · PI HUMPHREYS, BENJAMIN D. · 2015 to 2016
$626k
Extracellular Matrix Induction of Renal Stem and Progenitor Cell DevelopmentI01BX002660 · VA · SOUTHERN ARIZONA VA HEALTH CARE SYSTEM · PI WERTHEIM, JASON A · 2017 to 2020
–
BLRD VA I01 BX002660NIDDK NIH HHS DP3 DK108215NIDDK NIH HHS R24 DK106743NIDDK NIH HHS R37 DK054364NIDDK NIH HHS U01 DK094526NIDDK NIH HHS U01 DK107350NIDDK NIH HHS UH2 DK107343NIDDK NIH HHS UH2 DK107344NIDDK NIH HHS UH2 DK107357NIDDK NIH HHS UH2 DK107374NIDDK NIH HHS UH3 DK107357NIDDK NIH HHS UH3 DK107372
6 · The paper itself

Abstract

(Re)Building a Kidney is a National Institute of Diabetes and Digestive and Kidney Diseases-led consortium to optimize approaches for the isolation, expansion, and differentiation of appropriate kidney cell types and the integration of these cells into complex structures that replicate human kidney function. The ultimate goals of the consortium are two-fold: to develop and implement strategies for

Indexed as

Cell Culture TechniquesCell DifferentiationCell SeparationHumansInduced Pluripotent Stem CellsKidneyRegenerationTissue Culture TechniquesTissue ScaffoldsDirected differentiationOrganogenesisOrganoidRegeneration

Identifiers

PMID28096308
PMCPMC5407737
OpenAlexW2571734969

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.