Evidence map›Paper›PMID 28096253›Full record

SynthesisBMJ open2017

Generic prognostic factors for musculoskeletal pain in primary care: a systematic review.

Majid Artus, Paul Campbell, Christian D Mallen, Kate M Dunn, Danielle A W van der Windt

Registry-linked trialOpen access · goldAbstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in BMJ open, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07477145 (Effect of Body Mind Exercises and Specific Neck Exercises in Chronic Mechanical Neck Pain), which is not on this map. Cited by 93 papers, 12 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
93citing papers in PubMed, 12 pooled it
11.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07477145 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Effect of Body Mind Exercises and Specific Neck Exercises in Chronic Mechanical Neck Pain

TypeinterventionalSponsorCairo UniversityRan2026 to 2026Enrolled80ConditionsNeck Pain MusculoskeletalArmsConventional physical therapy group., Body mind exercises group (mindful aerobic exercises), specific neck exercise group, Combined exercise group.
3 · Its place in the literature

Who cites it

93 citing papers in PubMed, 12 syntheses or guidelines pooled it, 245 citations in OpenAlex.

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  6. Biopsychosocial Factors for Chronicity in Individuals with Non-Specific Low Back Pain: An Umbrella Review.International journal of environmental research and public health · 2022
    Pooled it
  7. Risk Factors to Persistent Pain Following Musculoskeletal Injuries: A Systematic Literature Review.International journal of environmental research and public health · 2022
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33 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Majid ArtusArthritis Research UK Primary Care Centre, Research Institute for Primary Care & Health Sciences, Keele University, Keele, UK.
Paul CampbellArthritis Research UK Primary Care Centre, Research Institute for Primary Care & Health Sciences, Keele University, Keele, UK.
Christian D MallenArthritis Research UK Primary Care Centre, Research Institute for Primary Care & Health Sciences, Keele University, Keele, UK.
Kate M DunnArthritis Research UK Primary Care Centre, Research Institute for Primary Care & Health Sciences, Keele University, Keele, UK.ORCID 0000-0002-6202-2606
Danielle A W van der WindtArthritis Research UK Primary Care Centre, Research Institute for Primary Care & Health Sciences, Keele University, Keele, UK.
Keele University · GB

Funding

Department of Health RP_2014-04-026Department of Health WMCLAHRC-2014-1
6 · The paper itself

Abstract

objectivesTo summarise the evidence for generic prognostic factors across a range of musculoskeletal (MSK) conditions.

settingprimary care. METHODS AND OUTCOMES: Comprehensive systematic literature review. MEDLINE, CINAHL, PsychINFO and EMBASE were searched for prospective cohort studies, based in primary care (search period-inception to December 2015). Studies were included if they reported on adults consulting with MSK conditions and provided data on associations between baseline characteristics (prognostic factors) and outcome. A prognostic factor was identified as generic when significantly associated with any outcome for 2 or more different MSK conditions. Evidence synthesis focused on consistency of findings and study quality.

results14 682 citations were identified and 78 studies were included (involving more than 48 000 participants with 18 different outcome domains). 51 studies were on spinal pain/back pain/low back pain, 12 on neck/shoulder/arm pain, 3 on knee pain, 3 on hip pain and 9 on multisite pain/widespread pain. Total quality scores ranged from 5 to 14 (mean 11) and 65 studies (83%) scored 9 or more. Out of a total of 78 different prognostic factors for which data were provided, the following factors are considered to be generic prognostic factors for MSK conditions: widespread pain, high functional disability, somatisation, high pain intensity and presence of previous pain episodes. In addition, consistent evidence was found for use of pain medications not to be associated with outcome, suggesting that this factor is not a generic prognostic factor for MSK conditions.

conclusionsThis large review provides new evidence for generic prognostic factors for MSK conditions in primary care. Such factors include pain intensity, widespread pain, high functional disability, somatisation and movement restriction. This information can be used to screen and select patients for targeted treatment in clinical research as well as to inform the management of MSK conditions in primary care.

Indexed as

AustraliaEuropeFemaleGeneral PracticeHumansMaleMusculoskeletal PainNorth AmericaPain MeasurementPrevalencePrognosisSeverity of Illness IndexPRIMARY CAREPrognosisPrognostic FactorsSystematic review

Identifiers

PMID28096253
PMCPMC5253570
OpenAlexW2577836604

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.