Evidence map›Paper›PMID 28096249›Full record

ArticleBMJ open2017

Natural language processing to extract symptoms of severe mental illness from clinical text: the Clinical Record Interactive Search Comprehensive Data Extraction (CRIS-CODE) project.

Richard G Jackson, Rashmi Patel, Nishamali Jayatilleke, Anna Kolliakou, Michael Ball, Genevieve Gorrell, Angus Roberts, Richard J Dobson, Robert Stewart

Open access · goldAbstract read
In one paragraph

Article in BMJ open, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 111 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
111citing papers in PubMed, 3 pooled it
17.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

111 citing papers in PubMed, 3 syntheses or guidelines pooled it, 233 citations in OpenAlex.

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51 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Richard G JacksonInstitute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.ORCID 0000-0002-3278-8547
Rashmi PatelInstitute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.ORCID 0000-0002-9259-8788
Nishamali JayatillekeInstitute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.
Anna KolliakouInstitute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.
Michael BallInstitute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.
Genevieve GorrellDepartment of Computer Science, University of Sheffield, Sheffield, UK.
Angus RobertsDepartment of Computer Science, University of Sheffield, Sheffield, UK.
Richard J DobsonInstitute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.ORCID 0000-0003-4224-9245
Robert StewartInstitute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.
King's College London · GBUniversity of Sheffield · GB

Funding

Medical Research Council MR/K002813/1
6 · The paper itself

Abstract

objectivesWe sought to use natural language processing to develop a suite of language models to capture key symptoms of severe mental illness (SMI) from clinical text, to facilitate the secondary use of mental healthcare data in research.

designDevelopment and validation of information extraction applications for ascertaining symptoms of SMI in routine mental health records using the Clinical Record Interactive Search (CRIS) data resource; description of their distribution in a corpus of discharge summaries.

settingElectronic records from a large mental healthcare provider serving a geographic catchment of 1.2 million residents in four boroughs of south London, UK.

participantsThe distribution of derived symptoms was described in 23 128 discharge summaries from 7962 patients who had received an SMI diagnosis, and 13 496 discharge summaries from 7575 patients who had received a non-SMI diagnosis. OUTCOME MEASURES: Fifty SMI symptoms were identified by a team of psychiatrists for extraction based on salience and linguistic consistency in records, broadly categorised under positive, negative, disorganisation, manic and catatonic subgroups. Text models for each symptom were generated using the TextHunter tool and the CRIS database.

resultsWe extracted data for 46 symptoms with a median F1 score of 0.88. Four symptom models performed poorly and were excluded. From the corpus of discharge summaries, it was possible to extract symptomatology in 87% of patients with SMI and 60% of patients with non-SMI diagnosis.

conclusionsThis work demonstrates the possibility of automatically extracting a broad range of SMI symptoms from English text discharge summaries for patients with an SMI diagnosis. Descriptive data also indicated that most symptoms cut across diagnoses, rather than being restricted to particular groups.

Indexed as

Electronic Health RecordsNatural Language ProcessingChronic DiseaseDatabases, FactualData CollectionHumansInformation Storage and RetrievalLondonMedical InformaticsMedical Informatics ApplicationsMental DisordersRegistriesclinical informaticsMENTAL HEALTHNatural Language ProcessingSerious Mental IllnessSymptomatology

Identifiers

PMID28096249
PMCPMC5253558
OpenAlexW2577646479

What OpenQuestion holds

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LicenceCC BY
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.