Evidence map›Paper›PMID 28096235›Full record

ArticleFASEB journal : official publication of the Federation of American Societies for Experimental Biology2017

Role of cardiotrophin-1 in the regulation of metabolic circadian rhythms and adipose core clock genes in mice and characterization of 24-h circulating CT-1 profiles in normal-weight and overweight/obese subjects.

Miguel López-Yoldi, Kimber L Stanhope, Marta Garaulet, X Guoxia Chen, Beatriz Marcos-Gómez, María Paz Carrasco-Benso, Eva M Santa Maria, Xavier Escoté, Vivien Lee, Marinelle V Nunez and 10 more

Registry-linked trialOpen access · bronzeAbstract readControlled Clinical Trial
PubMed Full text at PMC Publisher
In one paragraph

Article in FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03300388 (Dysfunction of Adipose Tissue in Obesity, Inflammation and Aging), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03300388 nacompletednot on this map

Dysfunction of Adipose Tissue in Obesity, Inflammation and Aging: Mechanisms and Effects of Physical Exercise and Omega-3 Fatty Acids.

TypeinterventionalSponsorClinica Universidad de Navarra, Universidad de NavarraRan2017 to 2019Enrolled85ConditionsObesity, Aging, InflammationArmsOmega-3 (DHA-rich dietary supplement), Placebo (olive oil), Resistance training
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Circulating Cardiac Biomarkers in Diabetes Mellitus: A New Dawn for Risk Stratification-A Narrative Review.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2020
    Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 5 institutions in 2 countries.

Miguel López-YoldiDepartment of Nutrition, Food Science, and Physiology, University of Navarra, Pamplona, Spain.
Kimber L StanhopeDepartment of Molecular Biosciences, School of Veterinary Medicine, University of California, Davis, Davis, California, USA.
Marta GarauletDepartment of Physiology, Faculty of Biology, University of Murcia, Murcia, Spain.
X Guoxia ChenDepartment of Molecular Biosciences, School of Veterinary Medicine, University of California, Davis, Davis, California, USA.
Beatriz Marcos-GómezDepartment of Nutrition, Food Science, and Physiology, University of Navarra, Pamplona, Spain.
María Paz Carrasco-BensoDepartment of Physiology, Faculty of Biology, University of Murcia, Murcia, Spain.
Eva M Santa MariaBiomedical Research Center for Hepatic and Digestive Diseases (CIBERehd) and Institute of Health Carlos III, Madrid, Spain.
Xavier EscotéDepartment of Nutrition, Food Science, and Physiology, University of Navarra, Pamplona, Spain.
Vivien LeeDepartment of Molecular Biosciences, School of Veterinary Medicine, University of California, Davis, Davis, California, USA.
Marinelle V NunezDepartment of Molecular Biosciences, School of Veterinary Medicine, University of California, Davis, Davis, California, USA.
Valentina MediciDepartment of Molecular Biosciences, School of Veterinary Medicine, University of California, Davis, Davis, California, USA.
Eduardo Martínez-AnsóDepartment of Hepatology and Gene Therapy, Center for Applied Medical Research (CIMA), University of Navarra, Pamplona, Spain.
Neira SáinzDepartment of Nutrition, Food Science, and Physiology, University of Navarra, Pamplona, Spain.
Ana E HuertaDepartment of Nutrition, Food Science, and Physiology, University of Navarra, Pamplona, Spain.
Laura M LaiglesiaDepartment of Nutrition, Food Science, and Physiology, University of Navarra, Pamplona, Spain.
Jesús PrietoBiomedical Research Center for Hepatic and Digestive Diseases (CIBERehd) and Institute of Health Carlos III, Madrid, Spain.
J Alfredo MartínezDepartment of Nutrition, Food Science, and Physiology, University of Navarra, Pamplona, Spain.
Matilde BustosDepartment of Hepatology and Gene Therapy, Center for Applied Medical Research (CIMA), University of Navarra, Pamplona, Spain.
Peter J HavelDepartment of Molecular Biosciences, School of Veterinary Medicine, University of California, Davis, Davis, California, USA.
Maria J Moreno-AliagaDepartment of Nutrition, Food Science, and Physiology, University of Navarra, Pamplona, Spain; mjmoreno@unav.es.
Universidad de Navarra · ESUniversity of California, Davis · USCentro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas · ESUniversidad de Murcia · ESInstituto de Salud Carlos III · ES

Funding

UC DAVIS CLINICAL AND TRANSLATIONAL SCIENCE CENTER: BPCAUL1RR024146 · NCRR · UNIVERSITY OF CALIFORNIA AT DAVIS · PI BERGLUND, LARS F · 2006 to 2011
$27.0M
Building Interdisciplinary Research Careers in Womens Health at UC Davis - Administrative SupplementK12HD051958 · NICHD · UNIVERSITY OF CALIFORNIA DAVIS · PI LANE, NANCY E · 2005 to 2023
$9.6M
Mouse Metabolic Phenotyping Center (MMPC) at UC DavisU2CDK092993 · NIDDK · UNIVERSITY OF CALIFORNIA AT DAVIS · PI LLOYD, KC KENT · 2016 to 2021
$5.9M
Mouse Metabolic Phenotyping Center (MMPC) at UC DavisU24DK092993 · NIDDK · UNIVERSITY OF CALIFORNIA AT DAVIS · PI LLOYD, KC KENT · 2011 to 2015
$4.1M
Fatty acid sources of fructose and HFCS-induced postprandial hypertriglyceridemiaR01HL107256 · NHLBI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI HAVEL, PETER J, SCHWARZ, JEAN-MARC · 2011 to 2014
$1.5M
MAST CELL MATRIX METALLOPROTEINASES IN LUNG REMODELINGF32HL009133 · NHLBI · UNIVERSITY OF CALIFORNIA SAN FRANCISCO · PI FANG, KENNETH C · 1994 to 1995
–
NCRR NIH HHS UL1 RR024146NHLBI NIH HHS F32 HL009133NHLBI NIH HHS R01 HL107256NICHD NIH HHS K12 HD051958NIDDK NIH HHS U24 DK092993NIDDK NIH HHS U2C DK092993
6 · The paper itself

Abstract

Cardiotrophin (CT)-1 is a regulator of glucose and lipid homeostasis. In the present study, we analyzed whether CT-1 also acts to peripherally regulate metabolic rhythms and adipose tissue core clock genes in mice. Moreover, the circadian pattern of plasma CT-1 levels was evaluated in normal-weight and overweight subjects. The circadian rhythmicity of oxygen consumption rate (

Indexed as

Circadian RhythmAdipose TissueAdolescentAdultAnimalsCLOCK ProteinsCytokinesFemaleHumansMaleMiceMice, Inbred C57BLObesityOxygen Consumptioncardiotrophin 1CLOCK ProteinsCytokinesadipose tissueBmal1Cry1obesityPer2

Identifiers

PMID28096235
PMCPMC5349803
OpenAlexW2572288704

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.