Evidence map›Paper›PMID 28096231›Full record

ArticleFASEB journal : official publication of the Federation of American Societies for Experimental Biology2017

Roles of 5-lipoxygenase and cyclooxygenase-2 in the biosynthesis of hemiketals E

Juan A Giménez-Bastida, Takahiro Shibata, Koji Uchida, Claus Schneider

Abstract read
In one paragraph

Article in FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Unusual and atypical cyclooxygenase reactions.The Journal of biological chemistry · 2026
    Review
  4. Review
  5. The Link between Prostanoids and Cardiovascular Diseases.International journal of molecular sciences · 2023
    Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Residual cyclooxygenase activity of aspirin-acetylated COX-2 forms 15 R-prostaglandins that inhibit platelet aggregation.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2019
    Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Juan A Giménez-BastidaDepartment of Pharmacology, Vanderbilt University Medical School, Nashville, Tennessee, USA.
Takahiro ShibataDivision of Biofunctional Chemistry, Graduate School of Bioagricultural Sciences, Nagoya University, Nagoya, Japan; and.
Koji UchidaDivision of Biofunctional Chemistry, Graduate School of Bioagricultural Sciences, Nagoya University, Nagoya, Japan; and.
Claus SchneiderDepartment of Pharmacology, Vanderbilt University Medical School, Nashville, Tennessee, USA; claus.schneider@vanderbilt.edu.
Nagoya University · JPVanderbilt Health · USVanderbilt University Medical Center · US

Funding

Translational Analysis CoreP30DK058404 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI RICHARD M. PEEK · 2002 to 2026
$29.9M
Convergence of the COX-2 and 5-lipoxygenase pathwaysR01GM076592 · NIGMS · VANDERBILT UNIVERSITY · PI SCHNEIDER, CLAUS · 2007 to 2021
$4.0M
Oxidative activation of the dietary cancer chemopreventive agent curcuminR01AT006896 · NCCIH · VANDERBILT UNIVERSITY · PI SCHNEIDER, CLAUS · 2013 to 2017
$2.2M
American Heart Association-American Stroke Association 16POST30690001NCCIH NIH HHS R01 AT006896NIDDK NIH HHS P30 DK058404NIGMS NIH HHS R01 GM076592
6 · The paper itself

Abstract

The 2 hemiketal (HK) eicosanoids HKD

Indexed as

Arachidonate 5-LipoxygenaseArachidonic AcidBlood PlateletsCalcimycinCyclooxygenase 2DinoprostoneHumansHydroxyeicosatetraenoic AcidsLeukocytesProstaglandin D25-hydroxy-6,8,11,14-eicosatetraenoic acidALOX5 protein, humanArachidonate 5-LipoxygenaseArachidonic AcidCalcimycinCyclooxygenase 2DinoprostoneHydroxyeicosatetraenoic AcidsProstaglandin D2PTGS2 protein, humanarachidonic acidleukotrieneprostaglandin

Identifiers

PMID28096231
PMCPMC5388546
OpenAlexW2575879005

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.