Evidence map›Paper›PMID 28096183›Full record

ArticleInfection and immunity2017

Pneumococcal Neuraminidase A (NanA) Promotes Biofilm Formation and Synergizes with Influenza A Virus in Nasal Colonization and Middle Ear Infection.

John T Wren, Lance K Blevins, Bing Pang, Ankita Basu Roy, Melissa B Oliver, Jennifer L Reimche, Jessie E Wozniak, Martha A Alexander-Miller, W Edward Swords

Open access · bronzeAbstract read
In one paragraph

Article in Infection and immunity, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 42 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Editorial: Reviews in microbial pathogenesis.Frontiers in microbiology · 2025
    Article
  5. Microbiology spectrum · 2024
    Article
  6. Article
  7. Article
  8. Pyrrolo[2,3-RSC advances · 2023
    Article
  9. Article
  10. Review
  11. Molecular epidemiology ofEpidemiology and infection · 2022
    Article
  12. Article
  13. Secondary infection withFEMS microbes · 2022
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Panel 1: Biotechnology, biomedical engineering and new models of otitis media.International journal of pediatric otorhinolaryngology · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

John T WrenDepartment of Microbiology and Immunology, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.
Lance K BlevinsDepartment of Microbiology and Immunology, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.
Bing PangDepartment of Microbiology and Immunology, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.
Ankita Basu RoyDepartment of Microbiology and Immunology, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.
Melissa B OliverDepartment of Microbiology and Immunology, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.
Jennifer L ReimcheDepartment of Microbiology and Immunology, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.
Jessie E WozniakDepartment of Microbiology and Immunology, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.
Martha A Alexander-MillerDepartment of Microbiology and Immunology, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.
W Edward SwordsDepartment of Microbiology and Immunology, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA swords@uab.edu.
Wake Forest University · USUniversity of Alabama at Birmingham · US

Funding

TRAINING PROGRAM IN IMMUNOLOGY AND PATHOGENESIST32AI007401 · NIAID · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI Martha Ann Alexander-Miller · 1991 to 2026
$4.4M
Microbial interactions in otitis mediaR01DC010051 · NIDCD · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI ORNELLES, DAVID ARNOLD, SWORDS, WILLIAM E · 2009 to 2018
$3.3M
NIAID NIH HHS T32 AI007401NIDCD NIH HHS R01 DC010051
6 · The paper itself

Abstract

Even in the vaccine era,

Indexed as

BiofilmsSymbiosisAnimalsBacterial AdhesionDisease Models, AnimalEnzyme ActivationFemaleInfluenza A virusMiceNasal MucosaNeuraminidaseOtitis MediaStreptococcus pneumoniaeNeuraminidasebiofilmsneuraminidaseotitis mediaStreptococcus pneumoniae

Identifiers

PMID28096183
PMCPMC5364304
OpenAlexW2573334603

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.