Evidence map›Paper›PMID 28096160›Full record

ArticleAntimicrobial agents and chemotherapy2017

Determinants of Antibacterial Spectrum and Resistance Potential of the Elongation Factor G Inhibitor Argyrin B in Key Gram-Negative Pathogens.

Adriana K Jones, Angela L Woods, Kenneth T Takeoka, Xiaoyu Shen, Jun-Rong Wei, Ruth E Caughlan, Charles R Dean

Open access · bronzeAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.3field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Regulation, structure, and activity of theAntimicrobial agents and chemotherapy · 2025
    Review
  4. The Structural and Molecular Mechanisms ofMolecules (Basel, Switzerland) · 2024
    Review
  5. Article
  6. The cyclic octapeptide antibiotic argyrin B inhibits translation by trapping EF-G on the ribosome during translocation.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  7. Effect of Ferredoxin Receptor FusA on the Virulence Mechanism ofFrontiers in cellular and infection microbiology · 2022
    Article
  8. Article
  9. Comparative Proteomic Analysis ofTurkish journal of pharmaceutical sciences · 2021
    Article
  10. Crystal Structure ofFrontiers in molecular biosciences · 2021
    Article
  11. Article
  12. Defects in Efflux (Antimicrobial agents and chemotherapy · 2019
    Article
  13. Article
  14. Article
  15. Mutations in GeneAntimicrobial agents and chemotherapy · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Adriana K JonesInfectious Diseases Area, Novartis Institutes for Biomedical Research, Emeryville, California, USA.
Angela L WoodsInfectious Diseases Area, Novartis Institutes for Biomedical Research, Emeryville, California, USA.
Kenneth T TakeokaInfectious Diseases Area, Novartis Institutes for Biomedical Research, Emeryville, California, USA.
Xiaoyu ShenInfectious Diseases Area, Novartis Institutes for Biomedical Research, Emeryville, California, USA.
Jun-Rong WeiInfectious Diseases Area, Novartis Institutes for Biomedical Research, Emeryville, California, USA.
Ruth E CaughlanInfectious Diseases Area, Novartis Institutes for Biomedical Research, Emeryville, California, USA.
Charles R DeanInfectious Diseases Area, Novartis Institutes for Biomedical Research, Emeryville, California, USA charlesr.dean@novartis.com.
Novartis (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Argyrins are natural products with antibacterial activity against Gram-negative pathogens, such as

Indexed as

AcinetobacterAnti-Bacterial AgentsBacterial ProteinsBurkholderiaDrug Resistance, BacterialMicrobial Sensitivity TestsOligopeptidesPeptide Elongation Factor GPseudomonas aeruginosaStenotrophomonas maltophiliaAnti-Bacterial Agentsargyrin BBacterial ProteinsOligopeptidesPeptide Elongation Factor GAcinetobacterantibacterialargyrinelongation factor GGram negativenatural productPseudomonas aeruginosaStenotrophomonas

Identifiers

PMID28096160
PMCPMC5365729
OpenAlexW2576628911

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.