Evidence map›Paper›PMID 28095819›Full record

ArticleBMC psychiatry2017

ADHD, comorbid disorders and psychosocial functioning: How representative is a child cohort study? Findings from a national patient registry.

Beate Oerbeck, Kristin Romvig Overgaard, Stian Thoresen Aspenes, Are Hugo Pripp, Marianne Mordre, Heidi Aase, Ted Reichborn-Kjennerud, Pal Zeiner

Open access · goldAbstract read
In one paragraph

Article in BMC psychiatry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 42 citations in OpenAlex.

  1. Youth with selective mutism: a nationwide patient registry study.European child & adolescent psychiatry · 2026
    Article
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  20. Adverse family life events during pregnancy and ADHD symptoms in five-year-old offspring.Journal of child psychology and psychiatry, and allied disciplines · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Beate OerbeckDivision of Mental Health and Addiction, Oslo University Hospital, Pb. 4959 Nydalen, 0424, Oslo, Norway. beate.orbeck@ous-hf.no.
Kristin Romvig OvergaardDivision of Mental Health and Addiction, Oslo University Hospital, Pb. 4959 Nydalen, 0424, Oslo, Norway.ORCID 0000-0002-8150-9030
Stian Thoresen AspenesThe Norwegian Patient Register, Trondheim, Norway.
Are Hugo PrippOslo University Hospital, Oslo Centre of Biostatistics and Epidemiology, Oslo, Norway.
Marianne MordreDivision of Mental Health and Addiction, Oslo University Hospital, Pb. 4959 Nydalen, 0424, Oslo, Norway.
Heidi AaseDivision of Mental Health, Norwegian Institute of Public Health, Oslo, Norway.
Ted Reichborn-KjennerudDivision of Mental Health, Norwegian Institute of Public Health, Oslo, Norway.
Pal ZeinerDivision of Mental Health and Addiction, Oslo University Hospital, Pb. 4959 Nydalen, 0424, Oslo, Norway.
Oslo University Hospital · NONorwegian Institute of Public Health · NO

Funding

Gene-Environment Interactions in an Autism Birth CohortU01NS047537 · NINDS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI LIPKIN, W. IAN · 2003 to 2013
$27.0M
NIEHS NIH HHS N01 ES075558NINDS NIH HHS U01 NS047537
6 · The paper itself

Abstract

backgroundCohort studies often report findings on children with Attention Deficit Hyperactivity Disorder (ADHD) but may be biased by self-selection. The representativeness of cohort studies needs to be investigated to determine whether their findings can be generalised to the general child population. The aim of the present study was to examine the representativeness of child ADHD in the Norwegian Mother and Child Cohort Study (MoBa).

methodsThe study population was children born between January 1, 2000 and December 31, 2008 registered with hyperkinetic disorders (hereafter ADHD) in the Norwegian Patient Registry during the years 2008-2013, and two groups of children with ADHD were identified in: 1. MoBa and 2. The general child population. We used the multiaxial International Classification of Diseases (ICD-10) and compared the proportions of comorbid disorders (axes I-III), abnormal psychosocial situations (axis V) and child global functioning (axis VI) between these two groups. We also compared the relative differences in the multiaxial classifications for boys and girls and for children with/without axis I comorbidity, respectively in these two groups of children with ADHD.

resultsA total of 11 119 children were registered with ADHD, with significantly fewer in MoBa (1.45%) than the general child population (2.11%), p < 0.0001. The proportions of comorbid axis I, II, and III disorders were low, with no significant group differences. Compared with the general child population with ADHD, children with ADHD in MoBa were registered with fewer abnormal psychosocial situations (axis V: t = 7.63, p < .0001; d = -.18) and better child global functioning (axis VI: t = 7.93, p < 0.0001; d = .17). When analysing relative differences in the two groups, essentially the same patterns were found for boys and girls and for children with/without axis I comorbidity.

conclusionsSelf-selection was found to affect the proportions of ADHD, psychosocial adversity and child global functioning in the cohort. However, the differences from the general population were small. This indicates that studies on ADHD and multiaxial classifications in MoBa, as well as other cohort studies with similar self-selection biases, may have reasonable generalisability to the general child population.

Indexed as

Interpersonal RelationsRegistriesAttention Deficit Disorder with HyperactivityChildCohort StudiesComorbidityFemaleHumansInternational Classification of DiseasesMaleMothersNeurodevelopmental DisordersNorwayProspective StudiesADHDChild psychiatryICD-10MoBaMultiaxial international classification of DiseasesNational patient registry

Identifiers

PMID28095819
PMCPMC5240379
OpenAlexW2577086014

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.