ArticleBMC psychiatry2017
Changes in event-related potentials in patients with first-episode schizophrenia and their siblings.
Article in BMC psychiatry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
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Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Facial emotion identification impairments in Chinese persons living with schizophrenia: A meta-analysis.Frontiers in psychiatry · 2022Pooled it
- Neurophysiological indices of face processing in people with psychosis and their siblings: An event-related potential study.The European journal of neuroscience · 2024Article
- The emotional facial recognition performance of Chinese patients with schizophrenia: An event-related potentials study.Indian journal of psychiatry · 2023Article
- Electrophysiological Studies of Reception of Facial Communication in Autism Spectrum Disorder and Schizophrenia.Review journal of autism and developmental disorders · 2022Article
- The Neural Correlates of Effortful Cognitive Processing Deficits in Schizophrenia: An ERP Study.Frontiers in human neuroscience · 2021Article
- Neurophysiological Face Processing Deficits in Patients With Chronic Schizophrenia: An MEG Study.Frontiers in psychiatry · 2020Article
- Neutral face and complex object neurophysiological processing deficits in long-term schizophrenia and in first hospitalized schizophrenia-spectrum individuals.International journal of psychophysiology : official journal of the International Organization of Psychophysiology · 2019Article
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13 authors.
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Abstract
backgroundThis study aimed to explore the characteristics of event-related potentials induced by facial emotion recognition in patients with first-episode schizophrenia and in their siblings.
methodsIn this case-control study, 30 first-episode schizophrenia patients, 26 siblings, and 30 healthy controls were enrolled. They completed facial emotion recognition tasks from the Ekman Standard Faces Database as an induction for evoked potentials. Evoked potential data were obtained using a 64-channel electroencephalography system. Average evoked potential waveforms were computed from epochs for each stimulus type. The amplitudes and latency of the event-related potentials for P100 (positive potential 100 ms after stimulus onset), N170 (negative potential 170 ms after stimulus onset), and N250 (fronto-central peak) were investigated at O1, O2, P7, and P8 electrode locations.
resultsThere were significant differences between the groups for P100 amplitude (F = 11.526, P < 0.001), electrode position (F = 450.592, P < 0.001), emotion (disgust vs. happiness vs. fear) (F = 1722.467, P < 0.001), and emotion intensity (low vs. moderate vs. high) (F = 1737.169, P < 0.001). Post hoc analysis showed significantly larger amplitudes in the schizophrenia group at the O1, O2, P7, and P8 electrode positions. There were no significant differences between the siblings of schizophrenia patients and the healthy controls.
conclusionsPatients with schizophrenia showed abnormalities in P100 amplitude, but similar results were not observed in their siblings. These results provide evidence of dysfunctional event-related potential patterns underlying facial emotion processing in patients with schizophrenia. P100 may be a characteristic index of schizophrenia.
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