Evidence map›Paper›PMID 28095642›Full record

ReviewGenesis (New York, N.Y. : 2000)2017

Maternal messages to live by: a personal historical perspective.

Mary Lou King

Abstract readReview
In one paragraph

Review in Genesis (New York, N.Y. : 2000), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Mary Lou KingDepartment of Cell Biology, University of Miami Miller School of Medicine, 1011 NW 15th St, Miami, Florida, 33136.

Funding

Role of Translational Regulators Nanos and Dazl in Preserving TotipotencyR01GM102397 · NIGMS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI KING, MARY LOU · 2013 to 2016
$1.5M
IDENTIFYING GERMLINE GENES AS TARGETS FOR THERAPEUTIC INTERVENTION IN CANCERR21HD072340 · NICHD · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI KING, MARY LOU · 2012 to 2013
$298k
NICHD NIH HHS R21 HD072340NIGMS NIH HHS R01 GM102397
6 · The paper itself

Abstract

In the 1980s, the study of localized maternal mRNAs was just emerging as a new research area. Classic embryological studies had linked the inheritance of cytoplasmic domains with specific cell lineages, but the underlying molecular nature of these putative determinants remained a mystery. The model system Xenopus would play a pivotal role in the progress of this new field. In fact, the first localized maternal mRNA to be identified and cloned from any organism was Xenopus vg1, a TGF-beta family member. This seminal finding opened the door to many subsequent studies focused on how RNAs are localized and what functions they had in development. As the field moves into the future, Xenopus remains the system of choice for studies identifying RNA/protein transport particles and maternal RNAs through RNA-sequencing.

Indexed as

AnimalsCell LineageMaternal InheritanceOocytesRNA, MessengerRNA, Messenger, StoredTransforming Growth Factor betaXenopus laevisXenopus ProteinsGDF1 protein, XenopusRNA, MessengerRNA, Messenger, StoredTransforming Growth Factor betaXenopus Proteinscytoplasmic determinantsgermlinelocalized RNAsXenopus

Identifiers

PMID28095642
PMCPMC5276792

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.