Evidence map›Paper›PMID 28095606›Full record

ArticleBritish journal of pharmacology2017

Endothelin-1 and its receptors on haemorrhoidal tissue: a potential site for therapeutic intervention.

Varut Lohsiriwat, John H Scholefield, Vincent G Wilson, Michael R Dashwood

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in British journal of pharmacology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Varut LohsiriwatDivision of Gastrointestinal Surgery, Queen's Medical Centre, University of Nottingham, Nottingham, UK.
John H ScholefieldDivision of Gastrointestinal Surgery, Queen's Medical Centre, University of Nottingham, Nottingham, UK.
Vincent G WilsonSchool of Life Sciences, Faculty of Medicine and Health Sciences, University of Nottingham, Nottingham, UK.
Michael R DashwoodRoyal Free Hospital Campus, University College Medical School, London, UK.
Queen's Medical Centre · GBUniversity College London · GBUniversity of Nottingham · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeHaemorrhoids is a common anorectal condition affecting millions worldwide. We have studied the effect of endothelin-1 (ET-1) and the role of endothelin ET EXPERIMENTAL APPROACH: Protein expression of ET-1, ET KEY

resultsDense binding of [ CONCLUSIONS AND IMPLICATIONS: ET

Indexed as

AutoradiographyBinding SitesBlotting, WesternEndothelin-1HemorrhoidsHumansImmunohistochemistryReceptors, EndothelinEndothelin-1Receptors, Endothelin

Identifiers

PMID28095606
PMCPMC5345667
OpenAlexW2578571980

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.