ArticlePloS one2017
Drosophila Genotype Influences Commensal Bacterial Levels.
Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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Who cites it
31 citing papers in PubMed.
- Host genetics and diet jointly shape the microbiome of Drosophila melanogaster but do not predict lifespan or age-related traits.Biogerontology · 2026Article
- Dietary allyl-isothiocyanate affects male triglyceride levels inFrontiers in microbiology · 2026Article
- Microbiome composition and co-occurrence dynamics in wildMicrobiology spectrum · 2025Article
- Kismet/CHD7/CHD8 affects gut microbiota, mechanics, and the gut-brain axis in Drosophila melanogaster.Biophysical journal · 2025Article
- Covariation Between Microbiome Composition and Host Transcriptome in the Gut of WildEcology and evolution · 2025Article
- Estimates of microbiome heritability across hosts.Nature microbiology · 2024Review
- A New Overview of Sex Bias in Fungal Infections.Journal of fungi (Basel, Switzerland) · 2024Review
- The role of animal hosts in shaping gut microbiome variation.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024Review
- Variable microbiomes between mosquito lines are maintained across different environments.PLoS neglected tropical diseases · 2023Article
- Gut Microbiome Transplants and Their Health Impacts across Species.Microorganisms · 2023Review
- Galbut Virus Infection Minimally InfluencesViruses · 2023Article
- Article
- Isolation, culture and characterization ofFrontiers in microbiology · 2023Article
- Gut microbe Lactiplantibacillus plantarum undergoes different evolutionary trajectories between insects and mammals.BMC biology · 2022Article
- Gut bacteria reflect the adaptation ofFrontiers in microbiology · 2022Article
- Natural diversity of the honey bee (Apis mellifera) gut bacteriome in various climatic and seasonal states.PloS one · 2022Article
- Long-term gut microbiome dynamics inProceedings. Biological sciences · 2021Article
- The microbiome extends host evolutionary potential.Nature communications · 2021Review
- Exposure to foreign gut microbiota can facilitate rapid dietary shifts.Scientific reports · 2021Article
- Dense time-course gene expression profiling of the Drosophila melanogaster innate immune response.BMC genomics · 2021Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
Host genotype can influence the composition of the commensal bacterial community in some organisms. Composition, however, is only one parameter describing a microbial community. Here, we test whether a second parameter-abundance of bacteria-is a heritable trait by quantifying the presence of four commensal bacterial strains within 36 gnotobiotic inbred lines of Drosophila melanogaster. We find that D. melanogaster genotype exerts a significant effect on microbial levels within the fly. When introduced as monocultures into axenic flies, three of the four bacterial strains were reliably detected within the fly. The amounts of these different strains are strongly correlated, suggesting that the host regulates commensal bacteria through general, not bacteria-specific, means. While the correlation does not appear to be driven by simple variation in overall gut dimensions, a genetic association study suggests that variation in commensal bacterial load may largely be attributed to physical aspects of host cell growth and development.
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