Evidence map›Paper›PMID 28095477›Full record

ArticlePloS one2017

The Burden of Mental Disorders in the Eastern Mediterranean Region, 1990-2013.

Raghid Charara, Mohammad Forouzanfar, Mohsen Naghavi, Maziar Moradi-Lakeh, Ashkan Afshin, Theo Vos, Farah Daoud, Haidong Wang, Charbel El Bcheraoui, Ibrahim Khalil and 73 more

Registry-linked trialOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05370443 (Effectiveness of an Online Life Skills-based Intervention on Depression, Anxiety and Stress Among Arabic Adolescents in Klang Valley, Malaysia), which is not on this map. Cited by 77 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
77citing papers in PubMed, 2 pooled it
18.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05370443 nacompletednot on this mapstarted 2022, after this paper: background citation

Effectiveness of an Online Life Skills-based Intervention on Depression, Anxiety and Stress Among Arabic Adolescents in Klang Valley, Malaysia: Protocol for a Cluster-randomized Controlled Trial

TypeinterventionalSponsorUniversiti Putra MalaysiaRan2022 to 2023Enrolled339ConditionsMental Disorder in AdolescenceArmsLife Skills education program
3 · Its place in the literature

Who cites it

77 citing papers in PubMed, 2 syntheses or guidelines pooled it, 183 citations in OpenAlex.

  1. Pooled it
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  5. Building Emotional Resilience in Youth in Lebanon: a School-Based Randomized Controlled Trial of the FRIENDS Intervention.Prevention science : the official journal of the Society for Prevention Research · 2020
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17 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

83 authors at 20 institutions in 28 countries.

Raghid ChararaInstitute for Health Metrics and Evaluation, Seattle, Washington, United States of America.
Mohammad ForouzanfarInstitute for Health Metrics and Evaluation, Seattle, Washington, United States of America.
Mohsen NaghaviInstitute for Health Metrics and Evaluation, Seattle, Washington, United States of America.
Maziar Moradi-LakehInstitute for Health Metrics and Evaluation, Seattle, Washington, United States of America.
Ashkan AfshinInstitute for Health Metrics and Evaluation, Seattle, Washington, United States of America.
Theo VosInstitute for Health Metrics and Evaluation, Seattle, Washington, United States of America.
Farah DaoudInstitute for Health Metrics and Evaluation, Seattle, Washington, United States of America.
Haidong WangInstitute for Health Metrics and Evaluation, Seattle, Washington, United States of America.
Charbel El BcheraouiInstitute for Health Metrics and Evaluation, Seattle, Washington, United States of America.
Ibrahim KhalilInstitute for Health Metrics and Evaluation, Seattle, Washington, United States of America.
Randah R HamadehArabian Gulf University, Manama, Bahrain.
Ardeshir KhosraviIranian Ministry of Health and Medical Education, Tehran, Iran.
Vafa Rahimi-MovagharSina Trauma and Surgery Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Yousef KhaderJordan University of Science and Technology, Irbid, Jordan.
Nawal Al-HamadPublic Authority for Food and Nutrition, Kuwait, Kuwait.
Carla Makhlouf ObermeyerCenter for Research on Population and Health, Faculty of Health Sciences, American University of Beirut, Beirut, Lebanon.
Anwar RafayContech International Health Consultants, Lahore, Pakistan.
Rana AsgharSouth Asian Public Health Forum, Islamabad, Pakistan.
Saleem M RanaContech International Health Consultants, Lahore, Pakistan.
Amira ShaheenDepartment of Public Health, An-Najah University, Nablus, Palestine.
Niveen M E Abu-RmeilehInstitute of Community and Public Health, Birzeit University, Ramallah, Palestine.
Abdullatif HusseiniInstitute of Community and Public Health, Birzeit University, Ramallah, Palestine.
Laith J Abu-RaddadHarvard University, Boston, MA, United States of America.
Tawfik KhojaHealth Ministers' Council for Cooperation Council States, Riyadh, Saudi Arabia.
Zulfa A Al RayessThe Saudi Center for Evidence Based Healthcare, Riyadh, Saudi Arabia.
Fadia S AlBuhairanKing Abdullah Specialized Children's Hospital, King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.
Mohamed HsairiMinistry of Health-Tunisia (Faculty of Medicine Tunis), Tunis, Tunisia.
Mahmoud A AlomariDivision of Physical Therapy, Department of Rehabilitation Sciences, Jordan University of Science and Technology, Irbid, Jordan.
Raghib AliUniversity of Oxford, Oxford, United Kingdom.
Gholamreza RoshandelGolestan Research Center of Gastroenterology and Hepatology, Golestan University of Medical Sciences, Gorgan, Iran.
Abdullah Sulieman TerkawiDepartment of Anesthesiology, University of Virginia, Charlottesville, VA, United States of America.
Samer HamidiHamdan Bin Mohammed Smart University, Dubai, United Arab Emirates.
Amany H RefaatSuez Canal University, Ismailia, Egypt.
Ronny WestermanFederal Institute for Population Research, Wiesbaden, Germany.
Aliasghar Ahmad KiadaliriClinical Epidemiology Unit, Department of Clinical Sciences Lund, Orthopedics, Lund University, Lund, Sweden.
Ali S AkandaUniversity of Rhode Island, Kingston, RI, United States of America.
Syed Danish AliSIR Consultants, Sindh, Pakistan.
Umar BachaSchool of Health Sciences, University of Management and Technology, Lahore, Pakistan.
Alaa BadawiPublic Health Agency of Canada, Toronto, ON, Canada.
Shahrzad Bazargan-HejaziDepartment of Psychiatry, Charles R. Drew University of Medicine and Science, Los Angeles, California, United States of America.
Imad A D FaghmousTehran University of Medical Sciences, Tehran, Iran.
Seyed-Mohammad FereshtehnejadDepartment of Neurobiology, Care Sciences and Society, Karolinska Institute, Stockholm, Sweden.
Florian FischerBielefeld University, Bielefeld, Germany.
Jost B JonasDepartment of Ophthalmology, Medical Faculty Mannheim, University Heidelberg, Heidelberg, Germany.
Barthelemy Kuate DefoDepartment of Social and Preventive Medicine, School of Public Health of the University of Montreal, Montreal, Quebec, Canada.
Alem MehariHoward University College of Medicine, Howard University, Washington DC, United States of America.
Saad B OmerEmory University, Atlanta, GA, United States of America.
Farshad PourmalekUniversity of British Columbia, Vancouver, BC, Canada.
Olalekan A UthmanWarwick-Centre for Applied Health Research and Delivery (WCAHRD), Division of Health Sciences, Warwick Medical School, University of Warwick, Coventry, United Kingdom.
Ali A MokdadDepartment of Surgery, University of Texas Southwestern, Dallas, Texas, United States of America.
Fadi T MaaloufDepartment of Psychiatry, American University of Beirut, Beirut, Lebanon.
Foad Abd-AllahDepartment of Neurology, Cairo University, Cairo, Egypt.
Nadia AkseerThe Hospital for Sick Children, Toronto, Canada; University of Toronto, Toronto, Ontario, Canada.
Dinesh AryaNorthern Territory Department of Health, Darwin, Northern Territory, Australia.
Rohan BorschmannCentre for Adolescent Health, Murdoch Children's Research Institute, Melbourne, Victoria, Australia.
Alexandra BrazinovaTrnava University, Trnava, Slovakia.
Traolach S BrughaUniversity of Leicester, Leicester, United Kingdom.
Ferrán Catalá-LópezDepartment of Medicine, University of Valencia/INCLIVA Health Research Institute and CIBERSAM, Valencia, Spain.
Louisa DegenhardtNational Drug and Alcohol Research Centre, University of New South Wales, Sydney, New South Wales, Australia.
Alize FerrariInstitute for Health Metrics and Evaluation, Seattle, Washington, United States of America.
Josep Maria HaroParc Sanitari Sant Joan de Déu-CIBERSAM, Sant Boi de Llobregat, Spain.
Masako HorinoNevada Division of Behavior and Public Health, Carson City, NV, United States of America.
John C HornbergerNational Institutes of Health, Bethesda, MD, United States of America.
Hsiang HuangCambridge Health Alliance, Cambridge, MA, United States of America.
Christian KielingFederal University of Rio Grande do Sul, Porto Alegre, Brazil.
Daniel KimDepartment of Health Sciences, Northeastern University, Boston, Massachusetts, United States of America.
Yunjin KimSouthern University College, Johor, Malaysia.
Ann Kristin KnudsenCentre for Disease Burden, Norwegian Institute of Public Health, Bergen, Norway.
Philip B MitchellSchool of Psychiatry, University of New South Wales, Sydney, New South Wales, Australia.
George PattonMurdoch Children's Research Institute, Department of Paediatrics, University of Melbourne, Melbourne, Victoria, Australia.
Rajesh SagarDepartment of Psychiatry, All India Institute of Medical Sciences, New Delhi, India.
Maheswar SatpathyUGC Centre for Advanced Studies in Psychology, Utkal University, Vani Vihar, Bhubaneswar, Odisha, INDIA.
Kim SavuonDepartment of Hospital Services, Ministry of Health, Phnom Penh, Cambodia.
Soraya SeedatDepartment of Psychiatry, Stellenbosch University, Stellenbosch, South Africa.
Ivy ShiueHealth and Life Sciences, Northumbria University, Newcastle upon Tyne, United Kingdom.
Jens Christoffer SkogenDomain for Mental and Physical Health, Norwegian Institute of Public Health, Bergen, Norway.
Dan J SteinDepartment of Psychiatry, University of Cape Town, Cape Town, South Africa.
Karen M TabbSchool of Social Work, University of Illinois at Urbana-Champaign, Champaign, Illinois, United States of America.
Harvey A WhitefordUniversity of Queensland, Brisbane, QLD, Australia.
Paul YipCentre for Suicide Research and Prevention, The University of Hong Kong, Pok Fu Lam, Hong Kong.
Naohiro YonemotoDepartment of Biostatistics, School of Public Health, Kyoto University, Kyoto, Japan.
Christopher J L MurrayInstitute for Health Metrics and Evaluation, Seattle, Washington, United States of America.
Ali H MokdadInstitute for Health Metrics and Evaluation, Seattle, Washington, United States of America.
Institute for Health Metrics and Evaluation · USNorwegian Institute of Public Health · NOThe University of Queensland · AUBirzeit University · PSCairo University · EGCambridge Health Alliance · USJordan University of Science and Technology · JOKyoto University · JPMinistry of Health · KHNortheastern University · USThe University of Melbourne · AUUniversity of Trnava · SKAll India Institute of Medical Sciences · INAmerican University of Beirut · LBAn-Najah National University · PSArabian Gulf University · BHBielefeld University · DEEmory University · USFederal Institute for Population Research · DEGolestan University · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Eastern Mediterranean Region (EMR) is witnessing an increase in chronic disorders, including mental illness. With ongoing unrest, this is expected to rise. This is the first study to quantify the burden of mental disorders in the EMR. We used data from the Global Burden of Disease study (GBD) 2013. DALYs (disability-adjusted life years) allow assessment of both premature mortality (years of life lost-YLLs) and nonfatal outcomes (years lived with disability-YLDs). DALYs are computed by adding YLLs and YLDs for each age-sex-country group. In 2013, mental disorders contributed to 5.6% of the total disease burden in the EMR (1894 DALYS/100,000 population): 2519 DALYS/100,000 (2590/100,000 males, 2426/100,000 females) in high-income countries, 1884 DALYS/100,000 (1618/100,000 males, 2157/100,000 females) in middle-income countries, 1607 DALYS/100,000 (1500/100,000 males, 1717/100,000 females) in low-income countries. Females had a greater proportion of burden due to mental disorders than did males of equivalent ages, except for those under 15 years of age. The highest proportion of DALYs occurred in the 25-49 age group, with a peak in the 35-39 years age group (5344 DALYs/100,000). The burden of mental disorders in EMR increased from 1726 DALYs/100,000 in 1990 to 1912 DALYs/100,000 in 2013 (10.8% increase). Within the mental disorders group in EMR, depressive disorders accounted for most DALYs, followed by anxiety disorders. Among EMR countries, Palestine had the largest burden of mental disorders. Nearly all EMR countries had a higher mental disorder burden compared to the global level. Our findings call for EMR ministries of health to increase provision of mental health services and to address the stigma of mental illness. Moreover, our results showing the accelerating burden of mental health are alarming as the region is seeing an increased level of instability. Indeed, mental health problems, if not properly addressed, will lead to an increased burden of diseases in the region.

Indexed as

Global HealthHealth StatusAdolescentAdultAgedAged, 80 and overAge FactorsChildChild, PreschoolFemaleHumansInfantInfant, NewbornLife ExpectancyMaleMediterranean Region

Identifiers

PMID28095477
PMCPMC5240956
OpenAlexW2574709330

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.