ArticlePloS one2017
Fecal Fat Analyses in Chronic Pancreatitis Importance of Fat Ingestion before Stool Collection.
Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed.
- Assessment of exocrine pancreatic function in children and adolescents with direct and indirect testing.Frontiers in pediatrics · 2022Review
- Diarrhea due to SARS-CoV-2-Related Exocrine Pancreatic Insufficiency.Case reports in gastrointestinal medicine · 2021Article
- Article
- Challenges in the management of pancreatic exocrine insufficiency.World journal of gastrointestinal pharmacology and therapeutics · 2018Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveQuantitative determination of fecal fat still is the gold standard for measuring malabsorption. We evaluated the importance of standardized food intake before and under the collection of feces. MATERIAL AND
methodsIn a project, evaluating patients with suspected chronic pancreatitis (CP) and healthy volunteers (HC), stools were collected for 72 hours coupled to registration of nutritional intake over five consecutive days. Patient groups were created by a modified Layer score, which includes imaging findings, clinical parameters and pancreas function testing.
resultsWe found 12 patients with CP, 11 patients without CP and 13 healthy individuals in our database. Median fecal fat in CP patients was 12 g/day, in non-CP patients 5 g/day and in healthy controls 5 g/day. Median fat absorption coefficient was 81% in those with chronic pancreatitis, 92% in those without CP and 92% in healthy controls. Corresponding median fat intake was 65 g/day, 68 g/day and 81 g/day in the respective groups. Spearman Rank Order Correlation between fecal fat (g/d) and fat absorption coefficient in all study subjects (n = 36) was good (-0.88 (p<0.001)). When we stratified groups according to fat intake, correlation between fecal fat and fat absorption was also good (-0.86 to -0.95).
conclusionIn the diagnoses of fat malabsorption, calculating the ratio of fat absorption did not give additional information compared to fecal fat.
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